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Circulation Circulation Invertebrates: Gastrovascular cavity or circulatory system Circulation Circulation Gastrovascular Cavity Circulation Open Circulatory System Circulation Open Circulatory System Circulation Closed Circulatory System Circulation gills body tissues Circulation lungs body tissues Circulation Circulation Why? Circulation Why is each one an improvement? head and arms lungs digestive tract & liver kidneys trunk & legs Circulation Some vocabulary: atrium SA node ventricle AV node aorta systole superior vena cava diastole inferior vena cava stroke volume pulmonary artery heart murmur septum lymph semilunar valves What’s in blood? Plasma: •Mostly water •Ions (Na, K, Ca, Mg, Cl, CO3) •Proteins •Food & waste •Gasses •Hormones Cellular elements: •Red blood cells (transport) •White blood cells (immune) •Platelets (clotting). Clotting: Clotting: fibrinogen Clotting: prothrombin Clotting: platelets Clotting: torn edge Clotting: 1. Platelets adhere to collagen fibers in damaged tissue. Clotting: 2. Platelets form a temporary plug. Clotting: 3. Platelets release clotting factor Clotting: 3. Platelets release clotting factor 4. Clotting factor turns prothrombin into thrombin Clotting: 3. Platelets release clotting factor 4. Clotting factor turns prothrombin into thrombin 5. Thrombin turns fibrinogen into fibrin Clotting: 6. Fibrin reinforces the clot Clotting: 6. Fibrin reinforces the clot Why? Clotting: 6. Fibrin reinforces the clot Why have so many steps in the clotting process? 1. 2. 3. 4. 5. 6. Clotting: Platelets adhere to collagen fibers in damaged tissue Platelets form a plug Platelets release clotting factors Clotting factors turn prothrombin into thrombin Thrombin turns fibrinogen into fibrin Fibrin reinforces clot. Diseases of the Circulatory System: atherosclerosis (narrowing) arteriosclerosis (hardening) hypertension (high blood pressure) HDL & LDL (good & bad cholesterol) heart attack stroke hemophilia. A Few Facts About Respiration: Countercurrent Exchange Oxygen flows down a concentration gradient from water or air into blood. A Few Facts About Respiration: Countercurrent Exchange Oxygen flows down a concentration gradient from water or air into blood. Seawater Fish Blood A Few Facts About Respiration: Countercurrent Exchange Oxygen flows down a concentration gradient from water or air into blood. 100 % saturation 10 % saturation A Few Facts About Respiration: Countercurrent Exchange Oxygen flows down a concentration gradient from water or air into blood 100 % saturation 10 % saturation A Few Facts About Respiration: Countercurrent Exchange Water flows over the gills Blood flows through the gills 100 % saturation 10 % saturation A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 100% 10% A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 100% 80% 10% 30% A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 100% 80% 60% 10% 30% 50% A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 100% 80% 60% 55% 10% 30% 50% 55% A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 100% 80% 60% 55% 55% 10% 30% 50% 55% 55% A Few Facts About Respiration: Countercurrent Exchange Gas exchange stops when the saturation levels equalize. 55% A Few Facts About Respiration: Countercurrent Exchange But when blood flows the opposite way from water… A Few Facts About Respiration: Countercurrent Exchange But when blood flows the opposite way from water… 100% 10% A Few Facts About Respiration: Countercurrent Exchange But when blood flows the opposite way from water… 100% 80% 60% 40% 20% 10% A Few Facts About Respiration: Countercurrent Exchange But when blood flows the opposite way from water… 100% 80% 60% 40% 20% 90% 70% 50% 30% 10% A Few Facts About Respiration: Countercurrent Exchange The concentration gradient is maintained along the entire length. 100% 80% 60% 40% 20% 90% 70% 50% 30% 10% A Few Facts About Respiration: Countercurrent Exchange The concentration gradient is maintained along the entire length. 90% A Few Facts About Respiration: Ventilation of the Lungs •Mammals use negative pressure •Amphibians use positive pressure •Birds breathe through hollow bones as well as through lungs. A Few Facts About Respiration: Hemoglobin •Efficient carrier of oxygen •Ours contains iron; mollusks’ contains copper •The Bohr shift. Why? Why lower the affinity of hemoglobin for oxygen when pH goes down? .