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What do we know about blood? Different blood types Pumped by the heart Travels thru veins & arteries Transports gasses and nutrients Different types of blood cells Can’t LIVE without it leukocytes erythrocytes Erythrocytes (red blood cells) Red blood cells carry oxygen to body tissues and remove carbon dioxide They are red because they contain a protein called hemoglobin that is red in color Red blood cells are round and thinner in the middle, like a balloon that is partly filled with water. This lets them squeeze through tiny blood vessels without breaking Biconcave shape increases surface area to allow for more O2 to be carried Do not have a nucleus Are made from the red bone marrow RBCs contain Hemoglobin Protein that bonds with oxygen when in an oxygen rich environment Releases oxygen when reaches tissues low in concentration of oxygen For energy RBCs make ATP thru anaerobic processes so it doesn’t use the O2 it is transporting Leukocytes (white blood cells) Function as a defense system in the body Fight and kills germs that enter the body Much larger than red blood cells Fewer WBCs than RBCs Have a nucleus Can slip into and out of the blood vessels Leukocytes (white blood cells) Theleukocyte leukocytes pass out through the capillary walls & into the infected tissue They change shape to surround the germs. They produce enzymes to kill & digest them. Leukocytes live for only a short time. Dead leukocytes, dead germs and liquid form pus in the infected area Platelets Helps with the clotting of blood Produce tiny fibrin threads allowing them to stick together This “web” traps blood cells that harden and form a scab or clot Made in the red bone marrow Platelets Hemostasis Blood vessel injury Vasoconstriction Platelet plug A lot of cool biochemistry! Coagulation occurs Blood clotting is a positive feedback mechanism and usually occurs within 3 – 6 minutes Plasma Pale liquid portion of the blood – 90% water Acts as a solvent Transports soluble food molecules Transports waste products Contains hormones, antibodies, electrolytes, and plasma proteins Our blood is a fluid which links together all the parts & all the organs of the body. Its main functions include: • Transport oxygen, waste products and hormones • Regulate temperature, helping to reduce heat by taking blood to the body surface • Balance acidity, reducing the effect of lactic acid (in sporting activities) • Fight invaders Blood Fun Facts The average human has 5 litres of blood It takes about 20 seconds for a red blood cell to circle the body The only part of the body with no blood supply is the cornea, it take in O2 directly from the air One cubic milimeter of healthy blood contains about 5 million red blood cells – this is the “blood count” People who live in high altitudes will have a higher blood count because of the lower O2 levels Athletes often train at high altitudes to improve distance race performance BLOOD DOPING, done by some athletes, mimics this effect What is blood doping? Why would blood doping give an athlete an advantage? Why is it difficult to test for blood doping? Why is blood doping dangerous? In your composition book create a table that lists the four major components of blood, describes their structure and lists their functions. Refer to your book pages 340 to 347 What’s your Type? Blood type refers to features of the person’s red blood cells called antigens The ABO blood groups are the features most people know about In this group, there are 4 different types of red blood cells -- A, B, AB, and O each are a different antigen Type O is the most common (~45%); type AB is the least common (~4%) Type O blood can be given to all blood types What’s your Type? Blood types are also grouped as to whether or not the RBC has the “D antigen” AKA the Rh factor, the “D antigen” is named for the Rhesus monkey in which it was first discovered People who have the “D antigen” are Rh positive. People who lack the “D antigen” are Rh negative. Most people are Rh positive Rh negative blood can be transfused into either Rh type Why can’t someone with type B- blood be given type A+ blood? O+ OA+ AB+ BAB+ AB- 38% 7% 34% 6% 9% 2% 3% 1% O- is called the universal donor because it can be given to ALL blood types- explain Circulation AHS A H S Your body resembles a large roadmap. There are routes or “arteries” that take you downtown to the “heart” of the city and “veins” that take you to the outskirts of town. Blood Vessels : One Way Streets Blood Vessels resemble very long and skinny tunnels that are all through your body Arteries carry blood away from the heart Veins carry blood to the heart Capillaries connect the two and are the drop off & pick up point Vessel walls composed of elastic fibers and smooth muscle Why do you think the muscle is so much thicker in the artery? The elastic fibers increase its elastic strength & the smooth muscles can change the diameter of the lumen Why would the diameter of the lumen need to be changed? NORMAL CORONARY ARTERY Tunica intima Tunica media Tunica externa Semi-lunar valves stop the back flow of blood The leg and abdominal muscles help blood flow upwards from the feet to the heart A Vein – note the thin wall and the semi-lunar valve Where substances enter & leave the blood Large surface area to volume ratio allows rapid diffusion of substances between blood and cells No cell in the body is more than 2 cells away from a capillary cell Wall is single layer of highly permeable endothelium endothelium (one cell thick) lumen Approximately 10 micrometers in diameter Blood vessels and blood cells: The body’s transportation system Arteries hemoglobin oxyhemoglobin oxyhemoglobin Capillaries Veins 1. In your composition book create a table that lists the three major vessels of the circulatory system, describes their structure and lists their functions. 2. Color and label the diagram of an artery and glue it on the page with your table. Refer to your book pages 374 to 377 WE ARE IN THE LIBRARY TOMORROW – BRING YOUR BOOK!!