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MIT Biology Department 7.012: Introductory Biology - Fall 2004 Instructors: Professor Eric Lander, Professor Robert A. Weinberg, Dr. Claudette Gardel Courtesy of Jeremy. Used with permission. Answers to Jeremy’s Super Duper 7.012 Immunology Quiz Nomenclature antigens antibodies epitope or antigenic determinant Overview of the Immune System Humoral immune system involves Abs, B cells (also helper T cells and macrophages). Cellular or Cell-Mediated A Few Words about Antibodies (Abs) B, Bone Marrow 4, heavy, light disulfide bonds VDJ VJ 2 Humoral Immunity vacuole or phagolysosome MHC II B MHC II, TH, Thymus, T cell receptor T cell receptor Il-2 clone, TCR (T cell receptor) endocytosed, oligopeptides, vacuole or phagolysosome, MHC II Antigen Presenting Cells cytokines, clonally expand or proliferate, differentiate Plasma Cells ribosomes?, endoplasmic reticulum?, machines or factories! Memory Cells directed somatic mutation faster and stronger (higher antibody titers) Cellular Immunity MHC I, cytoplasm the virus, or viral peptides killer T or Cytotoxic T clone (or expansion) kills, perforin, membrane
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