Download Immune System Day 4

Immune System Day 4
"Treasure the love you
receive above all. It will
survive long after your good
health has vanished."
-Og Mandino
Today’s Agenda
Finish Non-specific immunity notes
Quiz
Specific immunity notes—obj. 9, 10
Bacterial leprosy infection just under skin.
“border line leprosy—numb centers
2. Phagocytic cells-macrophages
i. Phagocytes include macrophages and
neutrophils
ii. Phagocytes engulf and destroy pathogens
iii. Phagocytosis is enhanced when pathogens
surface is altered by antibodies or complement
proteins
iv. Cell killing is enhanced by respiratory burst
Obj. 6
3. Natural killer cells – attack and
lyse body cells infected by viruses
or that are cancerous.
Obj. 7 Inflammatory response
1. Skin & mucous membranes
2. Phagocytic cells
3. Natural killer cells
4.
Inflammatory response
– damaged tissues release
histamines
– Histamines make vessels leaky,
releasing phagocytes & clotting
factors
– Phagocytes engulf bacteria
– Platelets form clots
Obj. 7
Obj. 5 Nonspecific Defenses: things your
body uses to defend against ANYTHING
5. Antimicrobial substances
–Interferon
–Complement proteins
1.
2.
3.
4.
5.
Skin & mucous membranes
Phagocytic cells
Natural killer cells
Inflammatory response
Antimicrobial substances
Obj. 8 Fever
6. Fever
– Macrophages release pyrogens
– Hypothalamus elevates temperature
– Liver & spleen supply less iron
– Bacteria don’t grow well without iron
– Metabolism increases speeding repair.
105
98.6
Ready for a Quiz???
Objective 9
B & T cells come from bone
marrow.
B’s mature in bursa (bone)
T’s mature in thymus
Objective 10
Antigens are substances
capable of causing an immune
response.
variable region