Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
B T1D 80 15000 80 ns hi % pSTAT5 of CD25 10000 5000 0 60 40 20 0 40 60 p th y e s ra a hi D 40 20 10 20 30 40 months on immune therapy ff 0 SLE 100 Figure S3: Therapy and disease status do not correlate with response to IL-2 in CD25hi cells of the T1D, MS or SLE cohorts. Data from Figure 1A were analyzed against clinical parameters for the (A) T1D, (B-C) MS and (D) SLE cohorts. Statistical significance was determined using linear regression in (A, C) and a Mann Whitney test in (B). The mean pSTAT5 response is indicated for each group in (B, D). IL2RArs2104286 genotype is noted by solid black (A/A), solid grey (A/G) and open (G/G) symbols where measured in the T1D and MS cohorts. hi 80 60 40 20 n t y s e re n a l s k in in v , o p lv le rt u m e ro k s h ri ti s in 0 a % pSTAT5 of CD25 60 o o n T % pSTAT5 of CD25 R2=0.0515, ns 0 80 y 20 b 0 ri d a y s s in c e d ia g n o s is 2 R = 0 .0 0 0 0 1 C MS % pSTAT5 of CD25hi A a r th r itis p lu s