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BME, Biomedical Engineering Dr. Ozdamar, Chair CORAL GABLES CAMPUS Biomedical Atomic Force Microscopy Laboratory, Director: Dr. Ziebarth Mc Arthur Engineering Annex, Room MEA 170A Stem Cell and Mechanobiology Laboratory, Director: Dr. Huang, McArthur Engineering Annex, Room MEA 168 Orthopaedics Biomechanics Laboratory, Director: Dr. Jackson McArthur Engineering Annex, Room MEA 169 Neurosensory Engineering Laboratory, Director: Dr. Ozdamar, Co-director: Dr. Bohorquez McArthur Engineering Building, Room MEB 153 Biomedical Imaging Laboratory, Director: Dr. Zhao McArthur Engineering Annex, Room MEA 201A Scanning Electron Microscopy Laboratory (CoE), Director: Dr. Dauer McArthur Engineering Annex, Room MEA 201B MEDICAL SCHOOL CAMPUS Neuroprosthetics Research Group Director: Dr. Sanchez, Co-director: Dr. Prasad Rosenstiel Room RSMB-4080, Medical Campus Joint Bioengineering and Endourology Laboratory, Co-Director: Dr. Salas, Co-director: Dr. Leveillee Miller School of Medicine, 1400 NW 10th Ave, Suite 509 Tissue Engineering Laboratory, Director: Dr. Stabler Miller School of Medicine, Diabetes Research institute Sensory Neurophysiology Laboratory Director Dr. Rajguru Miller School of Medicine, Ear Institute Physiomimetic Microsystems Laboratory Director: Dr. Agarwal Miller School of Medicine, BioNIUM, Pathology DUAL LABORATORIES (Coral Gables and Medical Campuses) Biomaterials Laboratory, Director: Dr. Andreopoulos McArthur Engineering Building, Room MEB 144B Rosenstiel Room RSMB-8075A, Medical Campus Cartilage Tissue Engineering and Mesenchymal Stem Cells Laboratory, Director: Dr. Cheung McArthur Engineering Building, Room MEA 168 Miami VA Medical Center, Research Building Biomedical Optics Laboratory, Biomedical Design Laboratory Director: Dr. Manns, Co-director: Dr. Parel Director: Dr. Montero Educating Tomorrow's Technology for CareerAnnex, SuccessRoom MEA 170B Mc ArthurLeaders Engineering McArthur Engineering Building, Room MEA 201A Bascom Palmer Eye Institute, Miller Medical School Neuroprosthetics Research Group Dr. Sanchez and Dr. Prasad Computational Neural Decoding Neural Electrode Failure Analysis EEG Neural Activations in Spinal Cord Injury Clinical Trials in Spinal Cord Injury Brain-Computer Interface Controlled Functional Electrical Stimulation in Spinal Cord Injury Spinal Cord Computer Interface Educating Tomorrow's Technology Leaders for Career Success Stem Cell and Mechanobiology Laboratory Director: C.-Y. Charles Huang, Ph.D. Stem cells: chondrogenesis of adult stem cells, charaterization of dental stem cells, development of novel bioreactor technology Mechanobiology: mechanobiology of intervertebral disc and stem cells, impact injury of articular cartilage, mechanobiological model of soft tissue Human knee articular cartilage Dental Stem Cells Oct4 Drop tower for impact loading Chondrogenesis Compression bioreactor Control Nestin TGF -b1- After impact injury Sox2 SSEA4 TGF -b1+ Nanog Tra-1-60 Aggrecan Collagen II Educating Tomorrow's Technology Leaders for Career Success Subjected to mechanical loading after impact injury Sensory Neurophysiology Lab – Dr. Suhrud Rajguru Optical Neural Stimulation for basic science and neuroprosthetic applications Improving diagnosis and treatment of inner ear disorders Auditory and vestibular electrophysiology (above) and eye movements evoked by Infrared radiation of vestibular Neuriepithelium (side) Mechanisms of Neuroprotection Educating Tomorrow's Technology Leaders for Career Success Physiomimetic Microsystems Laboratory nano Ashutosh Agarwal, PhD (www.PMLaboratory.com) Engineering Tools Research Projects 10 µm CELLULAR BIOMECHANICS 1 mm HEART ON A CHIP 10 cm macro Educating Tomorrow's Technology Leaders for Career Success CARDIAC PATCHES Biomedical Engineering 2014 Dr. Ozdamar, Chair Supervisor Dr. Weizhao Zhao Medical Imaging Dr. Alicia Jackson Orthopedic Biomechanics Selected Project Titles 1. A-Mode Ultrasound for Image-guided surgery by computerized robot and general ultrasound application 2. MRI instrument and MRI image analysis for experimental neuroscience projects 1. Determination of Environmental Effects on Intervertebral Disc Cells 2. Measurement of Transport Properties of Orthopaedic Tissues Dr. Ashutosh Agarwal Biomimetics 1. Biomimetic Neuro-Muscular Junctions 2. Engineered Hydrogels for Stem Cell Culture Dr. Abhishek Prasad (Dr. Justin Sanchez) Neuromotor Engineering 1. Brain-Machine Interface Research 2. Neural-Electrode Interfaces 3. Wireless, Implantable Neural Recording Devices. Dr. Charles Huang Mechanobiology Engr. 1. Cartilage tissue engineering and energy metabolism of intervertebral disc cells 2. Impact injury of articular cartilage Dr. Herman Cheung Stem Cell Engineering Dr. Fabrice Manns Biooptics and lasers 1. The role of mechanic force on the differentiation of human adult stem cells into cartilage, bone and cardiomyocytes 2. Transplantation of adult stem cells to relieve pain caused by diabetic neuropathy in animal model 3. The effect of Vitamin D3 and HGF in bone differentiation in human mesenchymal stem cells 1. Optics of the eye and vision correction (LASIK, presbyopia, intraocular lenses) 2. Ophthalmic surgical and diagnostic devices (aberrometry, optical coherence tomography) Dr. Ray Montero Medical Device Design 1. 3D medical device prototyping 2. Scaffold design for tissue engineering Dr. Noel Ziebarth Tissue Structure / Function 1. Ocular biomechanics assessed through Indentation Testing 2. Solute diffusion in the lens in the lens via fluorescent recovery after photobleaching Dr. Ozcan Ozdamar Neurosensory Engineering 1. Auditory and visual electrophysiological monitoring (with Dr. Bohorquez) 2. Otoacoustic emission measurement system for hearing loss determination (with Drs. Bennett and Bohorquez) Dr. Jorge Bohorquez Medical Instrumentation 1. Anesthesia monitoring for awareness (with Drs. McNeer and Ozdamar) 2. Retinal stress testing system (with Drs. Porciatti and Ozdamar) Dr. Fotios Andreopoulos Biomaterials Dr. Cherie Stabler Tissue Engineering 1. Growth factor immobilization on 3-D scaffolds 2. Fabrication of electrospun scaffolds with defined architectures 1. Macroporous scaffolds and nano-scale coatings for islet transplantation 2. Oxygen generating biomaterials for cellular transplantation Dr. Suhrud Rajguru Sensory Neurophysiology 1. Infrared Neural Stimulation for basic science and neuroprosthetic applications 2. Improving diagnosis and treatment of inner ear disorders Educating Tomorrow's Technology Leaders for Career Success