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Early detection of an endometrial cancer on health
screening by PET/CT
Nan-Jing Peng, MD
Department Nuclear Medicine
Abstract:
Whole-body FDG-PET has been used to screen underlying
malignancy of health people for decades. Recently, PET/CT
has been advocated as a tool for improvement of diagnosis
by FDG-PET. We assessed the PET/CT results of
asymptomatic individuals for health screening in our PET
center. The final confirmation of cancer was based on
pathologic report. Here, a case of endometrial cancer was
presented.
PET/CT
There are several abnormal FDG-avid areas including :
1. two hot spots in the thyroid gland (SUV max early: 5.8, delayed: 10.5 on the left, and SUV max early: 4.0, delayed: 4.3 on the right).
2. diffuse high FDG uptake in the central portion of uterus (SUV max & mean: early: 10.3 & 9.2, delayed: 16 & 12.8).
Ancillary tumor markers and thyroid hormone tests were also performed, which showed all within normal limits.
Tracing her history, endometrial hyperplasia is noted for one and half a years.
Impression:
1. Certain lesions in the thyroid gland, especially the left one. Malignant tumor can’t be ruled out.
2. Compatible with endometrial hyperplasia. Malignancy can’t be completely ruled out.
Pathological diagnosis:
#08 Uterus, labelled "endocervix", D&C ----- Adenocarcinoma, endometroid type, FIGO grade 1
#01 Uterus, endometrium, ATH+BSO+BPLND+para-aortic LN sampling----Adenocarcinoma, endometrioid type, moderately
differentiated without lymph nodal metastasis