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Co-ordination Electrical messenger Chemical messenger Nervous System Neuron cytoplasm dendron nucleus cell membrane direction of nerve impulses axon nucleus of cell which makes the myelin sheath Nerve fiber Myelin Sheath •Protection of nerve fiber •Speed up impulse transfer Rest Potential -- + More + ion outside the nerone + 1. Na K pump + 2. K channel 3. Big - ions Action potential Action potential mechanism • Depolarization Stimulus to threshold Na channel open Inside nerone turn +ve. • Repolarization Potential rise inside nerone to max Na channel close More k channel open so hyperpolarised Rest potential established by na k pump. Na open Refractory period K open Na close synapse ending of axon secretes a chemical which diffuses into synapse and stimulates the next neurone to pass on the impulse the chemical is unstable and will be destroyed later Synapse Synapse mechanism Go Synaptic Cleft Neurotransmitter in vesicle release to cleft. It diffuse to another side and attach on surface receptor. Enzyme next to receptor break down. Transmitter Brain Reflex arc : sensory, association, motor neurones dorsal root ganglion receptor sensory neurone (pain) effector (muscle) motor neurone dorsal root (sensory nerve) association neurone spinal cord ventral root (motor nerve) white matter grey matter central canal spinal cord spinal nerve Peripheral Nervous System consist of cranial nerves and spinal nerves these nerves leave CNS and run out to every part of the body spinal nerve cranial nerve Spinal Cell Endocrine System Hormone concept Steroid concept Endocrine organs Hormone concept Hormone is chemical messenger. It required a fitted receptor. Hormone attaching to receptor calls response. Hormone concept 2 Hormone required blood vessel to transport to whole body. Water soluble hormone Water soluble hormone only attach to membrane receptor. Fat soluble hormone (steroid) Steroid can penetrate cell membrane and bind to internal receptor. Example of steroids Feedback mechanism Negative feedback reduce hormone production when effect of hormone expressed Endocrine and Exocrine Blood vessel Secretary duct Endocrine organs Adrenal gland Adrenalin Photo of adrenal gland Pancreas Islet of langerhans Thyroid gland Pituitary gland Control of endocrine system Hormone control hormone Nerve control hormone Anterior and Posterior Pituitary gland Posterior Anterior Photo of pituitary gland