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By Hanaa Tashkandi *20% of diabetic patients enter the hospitals for foot problems. *70% of major leg amputations are done in diabetic patients. *50% of patients will need a contralateral lower limb amputation within two years. Foot ulceration. Foot infection. Foot gangrene. **severe sepsis. **major tissue loss. **non reconstructable vascular disease. The energy expenditure in an amputated patient increase by 60%. So because of that insufficient , most of the amputated diabetic patients are bed or wheel chair bound. There are three compartments in the sole of the foot: -medial , lateral and central. -are separated by the medial and lateral septae. **The floor : the planter fascia . **The roof the interosseous muscles and metatarsal bones. Nerve supply : tibial nerve which enters the foot through the tarsal tunnel. And the sensibility is provided by the three terminal branches of the tibial nerve. The dorsum of the foot: supplied by the dorsalis pedis artery. The planter of the foot: Supplied by the medial and lateral planter arteries. The dorsalis pedis artery may be absent or rudimentary in 15% of the population. Peripheral neuropathy. Peripheral vascular disease. Hematological abnormalities. Immune system impairment. It is a multidisciplinary care,,, i.e.; general surgery. plastic surgery. vascular surgery. Evaluation should focus on three major areas; systemic CAD, pulmonary,renal,CVA. Infection. Neurological status. Endocrine control. Absolute indication for amputation: severe sepsis. marked tissue loss. critical cardiac and renal condition. previous experience with graft failure or thrombosis. Debridement . Drainage of abscess. Application of local antibacterial agents. 1- management of weight bearing areas of the foot. ---metatarsal heads. ---the heal defect. 2-non weight bearing areas. ---forefoot. ---instep region. ---posterior part of hindfoot (Achilles region) ---dorsum of the foot.