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BIOLOGY CONCEPTS & CONNECTIONS Fourth Edition Neil A. Campbell • Jane B. Reece • Lawrence G. Mitchell • Martha R. Taylor CHAPTER 28 Nervous Systems Modules 28.14 – 28.20 From PowerPoint® Lectures for Biology: Concepts & Connections Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings THE HUMAN BRAIN 28.14 The vertebrate brain develops from three anterior bulges of the neural tube • The vertebrate brain evolved by the enlargement and subdivision of three anterior bulges of the neural tube – Forebrain – Midbrain – Hindbrain • Cerebrum size and complexity in birds and mammals correlates with sophisticated behavior Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Embryonic Brain Regions Brain Structures Present in Adult Cerebrum (cerebral hemispheres; includes cerebral cortex, white matter, basal ganglia) Forebrain Diencephalon (thalamus, hypothalamus, posterior pituitary, pineal gland) Midbrain Midbrain (part of brainstem) Pons (part of brainstem), cerebellum Hindbrain Medulla oblongata (part of brainstem) Diencephalon Cerebral hemisphere Midbrain Midbrain Pons Cerebellum Hindbrain Medulla oblongata Spinal cord Forebrain Embryo one month old Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Fetus three months old Figure 28.14 28.15 The structure of a living supercomputer: The human brain Table 28.15 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Cerebrum Forebrain Thalamus Cerebral cortex Hypothalamus Pituitary gland Midbrain Pons Hindbrain Medulla oblongata Spinal cord Cerebellum Figure 28.15A Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Most of the cerebrum’s integrative power resides in the cerebral cortex of the two cerebral hemispheres Left cerebral hemisphere Corpus callosum Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Right cerebral hemisphere Basal ganglia Figure 28.15B 28.16 The cerebral cortex is a mosaic of specialized, interactive regions • The motor cortex sends commands to skeletal muscles • The somatosensory cortex receives information about pain, pressure, and temperature • Several regions receive and process sensory information (vision, hearing, taste, smell) Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • The association areas are the sites of higher mental activities (thinking) – Frontal association area (judgment, planning) – Auditory association area – Somatosensory association area (reading, speech) – Visual association area Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings FRONTAL LOBE PARIETAL LOBE Speech Frontal association area Taste Somatosensory association area Reading Speech Hearing Smell Auditory association area Visual association area Vision TEMPORAL LOBE OCCIPITAL LOBE Figure 28.16 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • In lateralization, areas in the two hemispheres become specialized for different functions – “Right-brained” vs. “left-brained” Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 28.17 Connection: Injuries and brain operations have provided insight into brain function • Much knowledge about the brain has come from individuals whose brains were altered through injury, illness, or surgery – The rod that pierced Phineas Gage’s skull left his intellect intact but altered his personality and behavior Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 28.17A • A radical surgery called hemispherectomy removes almost half of the brain – It demonstrates the brain’s remarkable plasticity Figure 28.17B Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 28.18 Several parts of the brain regulate sleep and arousal • Sleep and arousal are controlled by – the hypothalamus – the medulla oblongata – the pons – neurons of reticular formation Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Eye Reticular formation Input from touch, pain, and temperature receptors Input from ears Motor output to spinal cord Figure 28.18A • An electroencephalogram (EEG) measures brain waves during sleep and arousal • Two types of deep sleep alternate – Slow-wave (delta waves) and REM sleep Awake but quiet (alpha waves) Awake during intense mental activity (beta waves) Delta waves Asleep Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings REM sleep Delta waves Figure 28.18B, C 28.19 The limbic system is involved in emotions, memory, and learning • The limbic system is a functional group of integrating centers in the cerebral cortex, thalamus, and hypothalamus • It is involved in emotions, memory (short-term and long-term), and learning – The amygdala is central to the formation of emotional memories – The hippocampus is involved in the formation of memories and their recall Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Thalamus CEREBRUM Hypothalamus Prefrontal cortex Smell Olfactory bulb Amygdala Hippocampus Figure 28.19 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 28.20 The cellular changes underlying memory and learning probably occur at synapses • Memory and learning involve structural and chemical changes at synapses – Long-term depression (LTD) – Long-term potentiation (LTP) Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 1 Repeated Sending neuron action potentials Sending neuron Synaptic cleft 2 2 4 3 Ca2+ Receiving neuron Cascade of chemical changes Ca2+ 3 LTP Figure 28.20 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings