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PERIPHERAL NERVE SYSTEM 1. Spinal ganglia 2. Peripheral nerve 3. Nerve endings 4. Spinal cord 5. Meninges NERVE ENDINGS NERVE ENDINGS SENSORY (receptors) A. Disposition: 1. Interoceptors 2. Proprioceptors 3. Exteroceptors B. Feelings: 1. Pain 2. Pressure 3. Temperature… C. Structure: 1. Simple (free) 2. Compound (nonfree): encapsulated, noncapsulated SYNAPSES (chemical and electric) Structure Functions: excitatory, inhibiting Mediator: acetylcholine, adrenalin, bombesin … III. EFFECTORY (effectors) Motor Secretory Peripheral nerve Nerve Spinal ganglion NERVE ENDINGS • • • SENSORY (receptors) A. Disposition: 1. Interoceptors 2. Proprioceptors • 3. Exteroceptors B. Feelings: 1. Pain • • 2. Pressure • Temperature… C. Structure: 1. Simple (free) • • 2. Compound (nonfree): encapsulated, noncapsulated SYNAPSES (chemical and electric) • – – – • • • 3. Structure Functions: excitatory, inhibiting Mediator: acetylcholine, adrenalin, bombesin … EFFECTORY (effectors) Motor Secretory Paccinian body Synapses Spinal cord SPINAL CORD • • Gray matter: H-like inside, nerve cells aggregations (nuclei) White matter: outside, columns of nerve fibers • • • • Types of nerve cells Radicular – axons form the anterior root Funicular– axons form the white matter funiculi Inner – axons lie in gray matter • • Ventral horn of gray matter: 5 nuclei – multipolar motor radicular neurons • • Lateral horn: Nucleus intremediolateralis – multipolar associative radicular neurons Nucleus intremediomedialis – multipolar associative funicular neurons • • • • Dorsal horn : Nucleus proprius – multipolar associative funicular neurons Nucleus thoracicus– multipolar associative funicular neurons MENINGES • 3 protective coats of CNS: dura, arachnoid and pia • Skull bone • Periosteum of skull • epidural space • DURA MATER – dense connective tissue • epithelium • subdural space • ARACHNOID – flat epithelium • fibrocollagenous tissue • web-like strands • subarachnoid space • PIA MATER – squamous epithelium • – loose connective tissue with blood vessels and nerve fibers • Basement membrane • Glia limitans (astrocytes) • Nerve tissue