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Development of the central
nervous system
Sanjaya Adikari
Department of Anatomy
Neural tube
& cavity
Development of brain
1
Prosencephalon
(forebrain)
1a
1b
2
Mesencephalon
(midbrain)
2
3
Rhombencephalon
(hindbrain)
3a
3b
1a
1b
Telencephalon
Cerebral hemispheres
Diencephalon
Thalamus, hypothalamus
subthalamus, epithalamus
2
3a
3b
Midbrain
Metencephalon
Myelencephalon
tectum, tegmentum and
cerebral pedunculi
pons, upper medulla
and cerebellum
lower medulla
Lateral ventricle
Foramen of Monro
3rd ventricle
Aqueduct
4th ventricle
Central canal of SC
Development of spinal cord and
brain stem
Mantle layer
Marginal layer
Neuroepithelial layer
1
Neuroblast cells
Neurons
Neuroepithelial cells
2
Gliablast cells
Glial cells
Ependymal cells
Oligodendroglia
Astroglia
Microglia
Mantle layer
Alar plate (sensory)
Marginal layer
Sulcus limitans
Neuroepithelial layer
Basal plate (motor)
Sensory
Motor
Posterior horn
Lateral horn
Sensory
Motor
Anterior horn
SE
BE
VE
VA
BA
GSA