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Transcript 
The hypothalamo-hypophyseal
systems.
The pituitary gland
Regulation of endocrine organs
Közp.
idegr.
Neurosecretion: secreration of neruon
gets into the bloodstream
Releasing
hormon (pl. CRF)
Adenohypophysis
sejt (pl. corticotrop)
Glandotrop hormon
(pl. ACTH)
Negative feedback: hormons of target
organ inhibit the adenohypophysis
Pituitary gland: parts
- Median eminence
Embryology: Rathke’s pouch + floor of diencephalon
Problem: craniopharyngioma tumors
Acidophil: GH, PROL
Secreted hormone
Abbreviation
Effect
Magnocellular Uterine contraction
neurosecretory Lactation (letdown reflex)
cells
Oxytocin
Vasopressin
(antidiuretic hormone)
Produced by
ADH
Increase in the permeability to water of the cells of distal
Magnocellular
tubule and collecting duct in the kidney and thus allows
neurosecretory
water reabsorption and excretion of concentrated urine
neurons
Portal circulation
Secreted hormone
Thyrotropin-releasing
hormone
Dopamine
(Prolactin-inhibiting hormone)
Growth hormone-releasing
hormone
Somatostatin
(growth hormone-inhibiting
hormone)
Gonadotropin-releasing
hormone
Corticotropin-releasing
hormone
Abbreviation Produced by
Effect
TRH, TRF, or Parvocellular Stimulate thyroid-stimulating hormone (TSH) release from
neurosecretory
PRH
anterior pituitary (primarily)
neurons
DA or PIH
GHRH
arcuate nucleus
Arcuate
nucleus
Inhibit prolactin release from anterior pituitary
Stimulate Growth hormone (GH) release from anterior
pituitary
SS, GHIH, or Periventricular Inhibit Growth hormone (GH) release from anterior pituitary
nucleus
Inhibit thyroid-stimulating hormone (TSH) release from anterior pituitary
SRIF
GnRH or
LHRH
CRH or CRF
Preoptic area
Parvocellular
neurosecretory
neurons
Stimulate follicle-stimulating hormone (FSH) release from
anterior pituitary
Stimulate luteinizing hormone (LH) release from anterior
pituitary
Stimulate adrenocorticotropic hormone (ACTH) release from
anterior pituitary
(1) Chromophils
Acidophils
- Somatotrophs
- Mammotrophs
Basophils
- Thyrotrophs
- Corticotrophs
- Gonadotrophs
(2) Chromophobes
Herring bodies (Gömöri / chrome haematoxylin phloxine)
3.: Bitemporal hemianposia
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