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BI 203 Human Anatomy & Physiology II
How is urine concentrated?
How/why does water
leave the proximal
tubule?
How/why does water
leave the descending
loop of Henle?
?
?
BI 203 Human Anatomy & Physiology II
How is urine concentrated?
How/why does water
leave the distal tubule?
How/why does water
leave the collecting
ducts?
?
?
BI 203 Human Anatomy & Physiology II
How is urine concentrated?
Concentration of urine is
dependent on the
concentration gradient
existing in the kidneys.
2) ________________:
Maintained 3 ways
Network of capillaries
carrying blood in
___________________
of nephron flow
1) _________________:
3) ________:
Both H2O and solutes are
lost from loop of Henle
(__________________
____________________).
Diffuses into _________
________________…
impermeable until
collecting duct… ______
_______________
BI 203 Human Anatomy & Physiology II
How is urine concentrated?
BI 203 Human Anatomy & Physiology II
How is urine concentrated?
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
80% of reabsorption is _____________
20% regulated via ________________
Who?
You
What?
Where? Posterior pituitary
When?
Changes in _______ and __________
Why?
Maintain homeostasis
How?
Cause formation of _____________
in __________ and _____________
BI 203 Human Anatomy & Physiology II
Take 2!!!
Ethyl alcohol (found in alcoholic
beverages) inhibits ADH secretion.
Since this is so, why/how does
consumption of an alcoholic
beverage influence urine
production?
Discuss with your
neighbor and predict
an answer.
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
80% of reabsorption is obligatory
20% regulated via hormonal control
Who?
You
What?
Where? Kidneys, blood
When?
Changes in pressure and osmolality
Why?
Maintain homeostasis
How?
_____ causes ultimate formation of ___________
which is a __________ AND causes secretion of
______________
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
80% of reabsorption is obligatory
20% regulated via hormonal control
Who?
You
What?
Where? Adrenal glands
If LOW levels of
aldosterone what
happens to “salt”
levels in filtrate?
What happens to
osmotic potential?
When?
______________________ and osmolality
Why?
Maintain homeostasis
How?
______________ causes increase in ________
__________ in _________ and ______________.
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
80% of reabsorption is obligatory
20% regulated via hormonal control
Who?
You
What?
What effect
does this
have on
blood
volume?
Where? Right atrium of heart
When?
High blood volume stretches the chamber
Why?
Maintain homeostasis
How?
____________________ inhibits the secretion of
_____ and the ______________________ (it also
dilates vessels).
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
Who?
You
What?
Where? Afferent arteriole
When?
Changes in blood pressure
Why?
Maintain homeostasis
How?
Dilate or restrict afferent arteriole. Controls what
pressure?
BI 203 Human Anatomy & Physiology II
How is urine concentration regulated?
Who?
You
What?
Where? Small renal arteries and afferent arterioles
When?
Severe stress and/or cardiac shock
Why?
Appropriate resources
How?
_______________________ (including afferent
arterioles) What happens to filtration pressure?
BI 203 Human Anatomy & Physiology II
How is “urine” produced artificially?
2 main types:
•___________
•___________
____________
BI 203 Human Anatomy & Physiology II
What is involved with micturition?
1) ____________
___________
2) _______
________ signal
_________ &
________
3) Bladder
________ and
internal sphincter
________
4) __________
______________
Bladder Incontinence!
BI 203 Human Anatomy & Physiology II
What are some kidney diseases/disorders?
Nephritis (acute and chronic)
Renal failure (acute and chronic)
Kidney stones (renal caliculi)
Incontinence (nerve damage,
gestational)
Urinary tract infection (cystitis,
urethritis)
Diuretics
BI 203 Human Anatomy & Physiology II
Let’s practice some renal histology!
BI 203 Human Anatomy & Physiology II
Let’s practice some renal histology!
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