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CH 9 Smooth Muscle Tissue J.F. Thompson, Ph.D. Smooth Muscle Cells • nonstriated = smooth • uninucleate Smooth Muscle Tissue • Lacks the dense fibrous connective tissue sheaths of skeletal muscles, but have delicate endomysium • Found in the walls of hollow internal organs (except the heart) • Often organized into two antagonistic layers (longitudinal and circular) oriented perpendicular to each other Characteristics of Smooth Muscle • Found in the walls of hollow internal structures (digestive, respiratory, reproductive tracts, blood vessels) • Arrector pili, pupil of the eye, etc. • Involuntary (unconscious) • Long, slow contractions, non-fatigable Smooth Muscle Tissue Smooth Muscle Tissue • May be autorhythmic • May have gap junctions • Dense bodies are cytoskeletal anchors • Myosin and Actin myofilaments are responsible for contraction Smooth Muscle Tissue • When the longitudinal layer contracts, the organ dilates and shortens • When the circular layer contracts, the organ constricts and elongates Contractions of Smooth Muscle • Peristalsis – alternating contractions and relaxations of smooth muscles that squeeze substances through the lumen of hollow organs • Segmentation – contractions and relaxations of smooth muscles that mix substances in the lumen of hollow organs Contractions of Smooth Muscle • Some smooth muscle cells: – Act as pacemakers and set the contractile pace for whole sheets of muscle – Are self-excitatory and contract without external stimuli • Whole sheets of smooth muscle exhibit slow, synchronized contractions – They contract in unison, reflecting their electrical coupling with gap junctions Regulation of Smooth Muscle • Contracts under the influence of: – Autonomic Nervous System – Hormones – Local regulatory factors End CH 9 Smooth Muscle Tissue