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Skeletal tissues 1. Classification and functions 2. Chondroid tissue cells, inter-cellular substance 3. Histogenesis of cartilages 4. Cartilages: a) hyaline; b) elastic; c) fibrocartilage 5. Bony tissue cells, intercellular substance 6. Fibrous bones 7. Lamellar bones 8. Long bones 9. Osteogenesis Skeletal tissues Chondroid tissue – Hyaline – Elastic – Fibrocartilage Bony tissue Fibrous bone Lamellar bone: a) cancellous b) compact Functions • • • • • 1. Supportive 2. Mechanical 3. Protective 4. Ca and P deposition 5. Water-mineral metabolism Chondroid tissue Cells + intercellular substance (chondromucoid, chondrine fibers) 1. Has no vessels 2. Intercellular components are predominant 3. Chondromucoid 70-80 % H2O 10-15 % org. 4-7 % mineral 4. Chondrine fibers – Collagen II – Elastic Chondroid tissue differon I Stem cell II Hemistem cells III Chondroblasts IV Chondrocytes Chondroclasts Differon stem cell hemistem cell chondroblasts chondrocytes Cartilage Hyaline cartilage Elastic cartilage Resorcin stain Fibrocartilage Bony tissue cells + matrix (osteoid+ossein fibers+salts) 1. 2. 3. 4. 5. Supports fleshy structures Protects organs Harbors the bone marrow Storage of Ca and P Multiply the forces of skeletal muscle contraction Osteocyte Osteoclast Bones 1. Fibrous 2. Lamellar (compact and cancellous) Diaphysis Haversian system Histogenesis 1. Intramembranous 2. Endochondral 1. Osteogenic islet 2. Osteoid stage 3. Salts impregnation 4. Replacement by lamellar bone Endochondral histogenesis Endochondral ossification 1. Cartilage model 2. Perichondral ossification 3. Endochondral ossification 4. Epiphyseal ossification Epiphyseal plate Regeneration Joint Joint Regulation