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Future of plastic surgery Z. Kruppa plastic surgeon Medisch Esthetisch Instituut Amsterdam Club of Amsterdam Amsterdam Fashion Institute 22 January 2009 Future of plastic surgery Plastic surgery Improvement of the quality of life Reconstructing the functional integrity Restoring the aesthetic appearance Refined techniques and instruments Construction and creativity Plastic surgery Technical innovations • Tissue transfer Tissue transfer • Lipofilling – fat transplantation • Natural and long lasting • No allergic reactions • No foreign body reaction • Additional improvement on the donor site • Rejuvenating effect of the harvested stem sells (?) • Combination with other techniques • Applications: • Facial rejuvenation • Breast enlargement • Body contouring Technical innovations • Tissue transfer • Transplantation Transplantation Transplantation Transplantation Transplantation Technical innovations • Tissue transfer • Transplantation • Stem cells Stem cells Multipotencial cells are able to transform to any tissue cell Stem cell harvesting: Embrional stem cells (destruction of human embryos, immunological rejection) Genetic induction or reprogramming (the details of the regulation are quite unknown) Patients own stem cells – umbilical cord (limited number) Development Tissue repair Cancer Stem cells - application Tissue repair Cardiac muscle (heart infarct) Diabetes (insuline producing islet cells) Neurodegenerative diseases (Parkinson, Alzheimer) Brain and spinal cord damage Technical innovations • • • • Tissue transfer Transplantation Stem cells Tissue engineering Tissue engineering Human cells and biomaterial Substitution of organ transplantation Arteficial heart valves, pancreas, kidney, liver, cartilage and bones Possible combination with cloning and stem cells No immune reaction – no need for immunosuppression Tissue engineering Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering Genetic engineering Modification of the human DNA Changing or replacing the information Production of lacking hormones, growth factors, structural elements Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering • Cloning Cloning Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering • Cloning • Scarless healing Scarless healing Scarless healing Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering • Cloning • Scarless healing • Injectables and biomaterials Injectables, biomaterials Injectables, biomaterials Requirements for the fillers Safe Reliable Natural Predictable volume No long term side effect Long lasting Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering • • • • Cloning Scarless healing Injectables and biomaterials Lasers Lasers Selective destruction of various cells Tattoo removal Epilation Scar treatment Vascular malformations Collagen induction Photo-rejuvenation Lasers - future Fractional treatment Rejuvenation with less side effect. Lasers - future Technical innovations • • • • • Tissue transfer Transplantation Stem cells Tissue engineering Genetic engineering • • • • • Cloning Scarless healing Injectables and biomaterials Lasers Meso-therapy Meso-therapy Local application Higher concentration More effective Less complication Meso-therapy Lipolysis, cellulite Wrinkles, stretch marks Hair loss, alopecia Muscle and joint pain Meso-therapy Future improvements: Needleless mesotherapy Electrophoresis Jet-peel Moral considerations New fields in aesthetic surgery New age groups in plastic surgery Thank you for your attention!