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Undergraduate Program in Biology and Medicine Independent Research (395) Registered in Fall ‘08 (In order by Subject Area) Course Subject Area Student (Class / Major) Research Title Mentor Department BCH 395 (Biochemistry) Justin Boucher '10 BMB Steve Georas Pulmonary Critical Care Unit M&D BCH 395 (Biochemistry) Anjali Chandra ‘09 BBC/HIS BCH 395 (Biochemistry) Elodie Coutinho Fernandes ‘09 BBC “LPA2 Receptor as an Important Component of the IL-12 Negative Feedback Mechanism” ”The Role of N-Terminal Acetylation in ssa1p” “Generation of CBF5p Mutants for the Study of Box H/ACA RNP Function” Bogdan Polevoda Yi-Tao Yu Biochemistry / Biophysics Biochemistry / Biophysics BCH 395 (Biochemistry) Matthew Golder '10 CHM Jeffey Hayes Biochemistry / Biophysics BCH 395 (Biochemistry) Steffen John Haider ‘09 BBC Jason Heath '10 BBC “Effects of H2A Variant Containing Nucleosomes on Linker Histone H1 Binding” “Independent Research” Eric Phizicky “Characterization of TIA-1 U20 RNA” Clara L. Kielkopf Patricia Hinkle Biochemistry / Biophysics Biochemistry / Biophysics Pharmacology / Physiology BCH 395 (Biochemistry) BCH 395 (Biochemistry) Andrea Jakubowski ‘09 BBC BCH 395 (Biochemistry) Megan E Jenkins ‘09 BBC BCH 395 (Biochemistry) Aja Ezgi Kalkanoglu ‘09 BBC BCH 395 (Biochemistry) Molly Elizabeth Kelly ‘09 BBC BCH 395 (Biochemistry) Duk Soo Kim '10 BBC BCH 395 (Biochemistry) Kelly Sullivan '10 BBC BCH 395 (Biochemistry) Sarah Sushchyk '10 BBC BCH 395 (Biochemistry) Kevin Thomas Van Bortle ‘09 BBC BCH 395 (Biochemistry) Chase Weidmann ‘09 BBC BCH 395 (Biochemistry) Sarah Wessel '10 BBC BIO 395 (Biology) “Structural Characterization of the Melanocorin 2 Receptor MRAP Dependence of Surface Expression and Signaling Activity” “Correlation Studies of the Protein Fluctuations of Three Different GPCRs” Alan M. Grossfield Biochemistry / Biophysics “Effects of Estrogen Receptor (ER) Ligands Intracellular Levels of Era” Mesut Muyan Biochemistry / Biophysics “Isolation of Suppressors of Yeast trm44-Δ tan1-Δ dus2-Δ Mutants and of trm44-Δ tan1-Δ trm4-Δ Mutants” “Overexpression of Eukaryotic NAcetyltransferases in Bacterial Systems” Eric Phizicky Biochemistry / Biophysics Bogdan Polevoda Biochemistry / Biophysics “Identification of Potential Dimerization Deficient Mutants of the Ste2p G ProteinCoupled Receptor of Saccharomyces cerevisiae” “Blocking CGRP Receptor in MDA 231 BR Breast Cancer Cells” Mark Dumont Biochemistry / Biophysics Edward Brown Biochemistry / Biophysics Jeffery Hayes Biochemistry / Biophysics Elizabeth Grayhack Biochemistry / Biophysics Mark Dumont Biochemistry / Biophysics Mindy Lynn Altemose ‘09 BMG “Development of Cysteine Reactivity Assay to Monitor H2B:H4 Interface Stability in a Nucleosome” “Probing the Mechanism of Codon Specific Effects on Translation in Saccharomyces cerevisiae: a Search for Evidence of CoTranslational Decay of mRNA” “Identification of Potential Dimerization Deficient Mutants of the Ste2p G ProteinCoupled Receptor of Saccharomyces cerevisiae” “DPP / BMP Signaling and Evolution of BMP-Chordin Axis” David Lambert Biology BIO 395 (Biology) Margaret Grace Ball '11 SA / ANT “Survey of Apple and Aronia Diversity in the University of Rochester Woodlands” Justin Ramsey Biology BIO 395 (Biology) Matthew Brockway ‘09 BMG “The Molecular Characterization of Ten Klar Alleles” Michael Welte Biology Page 1 of 4 7/10/09 Course Subject Area Student (Class / Major) Research Title Mentor Department BIO 395 (Biology) Michael W Cypress '10 BMG Nitasha Dhiman '11 BIO “RNA Localization Elements in Llyanassa Embryos” “Observing the Distribution of Aronia and P. malus Trees in the University of Rochester Woodlands” “NHEJ Repair in Aging Organisms” David Lambert Biology Justin Ramsey Biology Vera Gorbunova Vera Gorbunova Biology Elaine Sia Biology Allen Orr Biology BIO 395 (Biology) BIO 395 (Biology) BIO 395 (Biology) Stephanie Maia Enner '11 UNC NICHOLAS Farris '10 BMG “DNA Double Strand Break Repair by NonHomologous End Joining Becomes Less Efficient as Humans Age” “The Role of Rad27p in Mitochondrial Base Excision Repair in Saccharomyces cerevisiae” “Courtship Difference Between Drosophila sechellia and D. mauritiana” Biology BIO 395 (Biology) Catelyn Halusic '10 BMG / SP BIO 395 (Biology) David Thaddeus Liebers ‘09 HIS/BEB BIO 395 (Biology) BIO 395 (Biology) “Assembly Of 30s Ribosomal Subunit” “Evolution Research” Gloria Culver John Werren Biology Biology BIO 395 (Biology) Dana Lord ‘09 BBC Marisa Dias Mendes ‘09 BMG Alison Ossip-Klein '10 UNC “Independent Research Fall 2008-UR Woodlands Big Tree Analysis” Justin Ramsey Biology BIO 395 (Biology) Sima Patel '11 BBC Elaine Sia Biology BIO 395 (Biology) Gabriel Joseph Perreault '11 BIO John Werren Biology BIO 395 (Biology) Benjamin Sabari '10 BMG “Analysis of APN1 and RAD27’s Role in Mitochondrial Base Excision Repair in S. cerevisiae” “Hybrid Incompatibility Between N. vitripennis and N. giraulti: The Role of ATPD” “The Efficiency of Non Homologous End Joining in Human Cells Decreases as a Process of Organismal Aging (Hypothesis)” Vera Gorbunova Biology BIO 395 (Biology) Stephen Supoyo '10 BMG Heinrich Jasper Biology BIO 395 (Biology) Justin Sysol ‘09 BEB “RNAi Knockdown of Genes Implicated in Mouse Tumorigenesis and of Genes Differentially Expressed at High Levels in Drosophila Intestinal Stem Cells Reveals that Many Play Important Roles in Drosophila Posterior Midgut Maintenance” “Hybrid Incompatibility Between Two Species of Nasonia Wasps: Is the Mitochondrial Ribosome Involved?” John Werren Biology BIO 395 (Biology) Laney J Widener ‘09 BIO/RLS Justin Ramsey Biology BIO 395 (Biology) IND 395 (Med Ctr Research) IND 395 (Med Ctr Research) Andrew Zhu '10 PSY Ritesh Agnihothri '10 BIO “Tree Diversity in Urban Woodlands: The Distribution of the Castanea dentata (American Chestnut)” “Independent Study in Plant Ecology” “NF - kB in Skin Disease” Justin Ramsey Brian Poligone Biology Dermatology M&D Neha Arora ‘09 BIO/HIS “Antigenic Reactivity of Auto Reactive 964 Antibodies in SLE & HIV” Ignacio Sanz Immunology/Rheum Unit M&D IND 395 (Med Ctr Research) Matthew Au ‘09 BMG “Independent Research on Cool-1 Glioblastoma Multiformes” Mark Noble Department of Biomedical Page 2 of 4 7/10/09 Course Subject Area Student (Class / Major) Research Title Mentor Department IND 395 (Med Ctr Research) Stephanie Marie Barnoff ‘09 PSY “Profile of Microglia Surrounding Plaques in a Mouse Model of Alzheimer’s Disease in the Context of Neuroinflammation” Michael O’Banion Neurology & Anatomy M&D IND 395 (Med Ctr Research) IND 395 (Med Ctr Research) IND 395 (Med Ctr Research) Richard Louis Dubois ‘09 BIO Henry Garcia ‘09 BMG “Molecular Biology Research” Jiyong Zhao “Filbrillarin Functions in D. melanogaster” Willis Li Department of Biomedical Biomedical Genetics Stephanie Herrlinger '10 BIO “Induced Sustained Striatal Neurogenesis As Treatment Strategy For Huntington’s Disease: Construction Of A Lentiviral Shuttle For Sustained Overexpression Of BDNF.” Richard Glor Biology IND 395 (Med Ctr Research) IND 395 (Med Ctr Research) Dayo Emmanuel Lukula ‘09 BIO Asnaketch Negussie ‘09 BIO “Dengue Virus” Xia Jin Xia Jin IND 395 (Med Ctr Research) Rachel Simpson ‘09 BMB “Human Brain Microvascular Endothelial Cells’ permissiveness to Dengue Virus Infection” “Dengue Virus Type 2 Infection Of CV-1 and Vero Cells” Infectious Disease Unit M&D Infectious Disease Unit M&D Xia Jin Infectious Disease Unit M&D MBI 395 (Microbiology / Immunology) Chris Hergott ‘09 BBC Kim Baek Microbiology & Immunology M&D MBI 395 (Microbiology / Immunology) Andrew Kim '11 CHM David Topham Micro. Center Vaccine Biology Immunology MBI 395 (Microbiology / Immunology) Drew Allan Phillips ’08 BMB “Steady State and Pre-Steady State Kinetics of the L409M PFU Polymerase Mutant and ITS Exonuclease Domain Variants” “Either Random or Pre-Destined: A Look at the Immune Response by Immunohistochemistry on ParaffinEmbedded and Frozen Tissue” “Oxidative Stress and Damage in the Oral Pathogen Streptococcus mutans” Robert Marquis Microbiology & Immunology M&D MBI 395 (Microbiology / Immunology) Stefanie Ashley Trop ’09 BMB, MUS “Radioprotection by Targeted SIRNA Delivery to Salivary Gland” Stephen Dewhurst Microbiology & Immunology M&D MBI 395 (Microbiology / Immunology) MBI 395 (Microbiology / Immunology) Jennifer (Wing-Wah) Tsang ‘09 PSY Victoria Vignare '10 BMG “Vibrio Cholerae VSP-II Excision and Transfer” “The Selection and Production of Fibronectin Monobodies that Show Specific Binding to a Variety of Antibodies” Michelle Dziejman Mark A. Sullivan NSC 395 (Brain & Neuroscience) Mihir Buch '10 BNS “Anatomical Analysis of the Visual System and Reaction Times for Sensing Stimuli” Robert Doty Microbiology & Immunology M&D Biochemistry & Biophysics Center for Oral Biology 601 Elmwood Avenue Ave. KMRB G-9627 Neurobiology and Anatomy M&D NSC 395 (Brain & Neuroscience) NSC 395 (Brain & Neuroscience) NSC 395 (Brain & Neuroscience) NSC 395 (Brain & Neuroscience) Aynsley Welsh Duncan ‘09 BNS Woong Hwang '11 UNC Microdialysis at the NBFC Troy Zarcone Environmental Medicine “Does Tau Self-Association Lead to Tau Toxicity” “The EZ Diffusion Model Analysis of Proximity Effect” “Bimodal Integration in MSTd to Compute Self-Movement” Gail Johnson Anesthesiology M&D Voyko Kavcic Cognitive Behavioral Neurology Brain & Cognitive Sciences NSC 395 (Brain & Neuroscience) Eve Privman ‘09 BNS / CHM “Astrocyte Health and Function” David Rempe NSC 395 (Brain & Neuroscience) Ajit Rao '10 BBC “Real-time in situ Kinetics of Dopamine Transporter Hyperactivity Induced by Platelet Activating Factor (PAF)” Harris A Gelbard Kwang Jun Lee ‘09 BNS Kwang Jun Lee ‘09 BNS Gregory Deangelis Neurology/Ctr Neural Development & Disorders Neurology Pediatrics M&D Page 3 of 4 7/10/09 Course Subject Area Student (Class / Major) Research Title Mentor Department NSC 395 (Brain & Neuroscience) PHP 395 (Pharmacology & Physiology) Aaron Prasad Varghese '10 BNS David Reiner '10 BNS “Neural Circuitry Zebra Finch” Raphael Pinaud Suzanne Haber Brain and Cognitive Sciences Pharmacology & Physiology “The Dopamine-Habenula Connection” Page 4 of 4 7/10/09