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Cat and Dog
Preventative Care and
Medicine II
Dr. N. Matthew Ellinwood, D.V.M., Ph.D.
January 18, 2012
IOWA STATE UNIVERSITY
COLLEGE OF AGRICULTURE AND LIFE SCIENCES
Distemper and Measles
• Cross reactive antibodies
– First vaccine
Parvo
•
•
•
•
•
•
Small DNA virus
World wide pandemic in dog in late 1970’s
Viral Enteritis
Virus requires rapidly dividing cells
GI and Immune tropism
Maternal antibodies among most persistent
Parvo Continued
• Crypt morphology
• Prognosis
• Therapy
CAV1 and CAV2
• CAV-1
– Cause of Infectious Canine Hepatitis
– Very rare to see due to vaccinal prophylaxis
– Can lead to chronic shedding and infection
• Kidney and liver
– Blue eye
• CAV-2
– Cause of infectious tracheobronchitis
– Vaccinal strains yield cross reactive antibodies
Parainfluenza
• A cause of infectious tracheobronchitis
–
–
–
–
Paramyxovirus
No replication in macrophages
Local infection of upper respiratory tract
Vaccinal prevention
Corona
• Targets mature epithelial cells of mucousa
• Usually a self limiting viral enteritis
• Discovered in 1971 in an outbreak of
military dogs
• Vaccinal prevention is incomplete
• Death is rare
– Young pups with fluid loss
• Supportive care
Papillomatosis
• CPV cause papillomas
– Young animals
– Sites
– Immunosuppressed animals
Versus
• Venereal transmissible tumor
Leptospira
•
•
•
•
•
•
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Environmental exposure
Wildlife and rodent reservoir
Shed in urine
Water sources
Type of dog at risk
Regional serovars
Vaccinal approach
– Bactarin
Brucella
•
•
•
•
Venereal
Reportable
Treatment difficulty/failure
Clincial signs
– Male
– Female
Herpes
•
•
•
•
•
•
Some characteristics of herpes virus
30% to 100% seropositivity
Infection
Adult
Pups
Prevention