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Cat and Dog Preventative Care and Medicine II Dr. N. Matthew Ellinwood, D.V.M., Ph.D. January 18, 2012 IOWA STATE UNIVERSITY COLLEGE OF AGRICULTURE AND LIFE SCIENCES Distemper and Measles • Cross reactive antibodies – First vaccine Parvo • • • • • • Small DNA virus World wide pandemic in dog in late 1970’s Viral Enteritis Virus requires rapidly dividing cells GI and Immune tropism Maternal antibodies among most persistent Parvo Continued • Crypt morphology • Prognosis • Therapy CAV1 and CAV2 • CAV-1 – Cause of Infectious Canine Hepatitis – Very rare to see due to vaccinal prophylaxis – Can lead to chronic shedding and infection • Kidney and liver – Blue eye • CAV-2 – Cause of infectious tracheobronchitis – Vaccinal strains yield cross reactive antibodies Parainfluenza • A cause of infectious tracheobronchitis – – – – Paramyxovirus No replication in macrophages Local infection of upper respiratory tract Vaccinal prevention Corona • Targets mature epithelial cells of mucousa • Usually a self limiting viral enteritis • Discovered in 1971 in an outbreak of military dogs • Vaccinal prevention is incomplete • Death is rare – Young pups with fluid loss • Supportive care Papillomatosis • CPV cause papillomas – Young animals – Sites – Immunosuppressed animals Versus • Venereal transmissible tumor Leptospira • • • • • • • Environmental exposure Wildlife and rodent reservoir Shed in urine Water sources Type of dog at risk Regional serovars Vaccinal approach – Bactarin Brucella • • • • Venereal Reportable Treatment difficulty/failure Clincial signs – Male – Female Herpes • • • • • • Some characteristics of herpes virus 30% to 100% seropositivity Infection Adult Pups Prevention