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West
Nile
Virus
West Nile Virus
The 2004 Picture
Washington State Department of Health
1
WNV Background
First isolated from in the West Nile District of
Uganda, 1937
Recognized as a cause of inflammation of
the spinal cord and brain with outbreak
in elderly patients, Israel, 1957
Equine disease noted in Egypt and France
in the early 1960s
1999 “Old World” virus arrives in the “New
World”
Washington State Department of Health
2
Transmission Cycle
Mosquito vector
Bird
reservoir
hosts
Washington State Department of Health
Incidental
infections
Incidental infections
3
WNV in the US
Some Speculated Pathways of
Introduction
Human-transported bird
Human-transported mosquitoes
Storm-transported bird
Intentional introduction (terrorist event)
- not likely
Infected human traveler - not likely
Washington State Department of Health
4
Human infection with WNV
1/150 of all infections
cause West Nile
neuroinvasive
disease (WNND)
<1%
WNND
~20%
West Nile fever
Fatal WNV infection:
<0.1% of all infections
10% of WNND
Very rough
estimates
~80%
No symptoms
Washington State Department of Health
5
Washington State Department of Health
6
Washington &WNV
2002 Washington goes positive...
Raven
Crow
Horse
Horse
Pend Oreille County
Snohomish County
Island County
Whatcom County
Washington State Department of Health
7
A Tale of Two Years
As of November 16
2003
2004
US Total
9,862
2,313
“The West”
3,773
1,562
Washington State Department of Health
8
A Tale of Two Years
2003
Arizona
California
Colorado
Idaho
Montana
Nevada
New Mexico
Oregon
Utah
Washington
Wyoming
Washington State Department of Health
2004*
13
389
3
2,947
1
737
276
2
222
2
209
6
44
86
0
1
0
3
11
0
375
9
*As of Nov 23, 2004
9
2004 WNV Cases as of November 23
Washington State Department of Health
10
West
Nile
Virus
The Northwest
Experience
Washington State Department of Health
11
Idaho
2003
2004
Humans
1
2
Horses
0
23
Birds
0
6
Washington State Department of Health
12
Idaho Human Case Locations 2004
Washington State Department of Health
13
Idaho Horse Case Locations 2004
Washington State Department of Health
14
Idaho Bird Case Locations 2004
Washington State Department of Health
15
Oregon
2003
2004
Humans
0
3
Horses
0
31
Birds
0
19
Washington State Department of Health
16
Oregon Human Case Locations 2004
Washington State Department of Health
17
Oregon Horse Case Locations 2004
Washington State Department of Health
18
Oregon Bird Case Locations 2004
Washington State Department of Health
19
Washington Bird Locations 2004
536 birds tested
Washington State Department of Health
20
Washington Surveillance Testing 2004
Humans
23
Horses
53
Birds
551
Mosquito Pools
829
Washington State Department of Health
21
Lasting Effects
47% required physical therapy after
hospitalization
Only 37% fully recovered after 1 year
Cognitive loss reported = 41.2%
Functional loss reported = 42.9%
Physical loss reported = 45.7%
Source: Emerging Infectious Diseases, Vol. 10, No. 8, August 2004
(http://www.cdc.gov/ncidod/EID/vol10no8/03-0879.htm)
Washington State Department of Health
22
West Nile Virus Surveillance
Thanks to Our Partners
•
•
•
•
•
•
Mosquito Control Districts
Local Health Jurisdictions
USACHPPM-West
Veterinarians
Health Care Providers
State agencies and others
Washington State Department of Health
23
West
Nile
Virus
Only Time Will
Tell
Washington State
Update 2004
Washington State Department of Health
24
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