Download Healthcare New Imaging Technologies Confidential KONICA MINOLTA, INC.

Confidential
Healthcare
New Imaging Technologies
KONICA MINOLTA, INC.
HEALTHCARE COMPANY
July, 2014
Confidential
Talbot-Lau Interferometry Images
(Super X-Ray)
ＪＳＴ（独立行政法人 科学技術振興機構）プロジェクト
Talbot-Lau Interferometry
Confidential
Imaging Apparatus
X-ray source Imaging object
G0
G1 Self-Image
Deformation
due to
imaging
object
G1
G2 Transmittance
X-ray detector
G2
Moiré Pattern
detected with X-ray detector
+
Signals due to
imaging object
3
Features of Images
Attenuation Contrast
Image(ATT)
 Conventional
radiography
image
Differential Phase
Contrast Image (DPC)
 Refractive
index gradient
Confidential
Small-Angle Scattering
Contrast Image(SAS)
 X-ray small-angle
scattering due to
microstructures
comparable to grating
pitch
4
Talbot-Lau Imaging System
X-ray tube
・Anode size：400μm
・Anode：tungsten
・Tube voltage：40kV
Object table
Confidential
Source
grating(G0)
・22.8μm cycle
Absorption
grating(G2)
・5.3μm cycle
Phase
grating(G1)
・4.3μm cycle
X-ray detector
・FPD
・Pixel size 85μm
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DPC Image of A Patient
Finger
- Comparison with MRI -
SAITAMA MEDICAL UNIVERSITY HOSPITAL
Confidential
Stage: Ⅱ
6
DPC Image of A Patient
Finger
- Comparison with MRI -
SAITAMA MEDICAL UNIVERSITY HOSPITAL
Confidential
Stage: Ⅲ
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DPC Image of A Patient
Finger
- Comparison with Normal Volunteer -
<normal volunteer>
<patient Stage Ⅱ>
Confidential
<patient Stage Ⅲ>
SAITAMA MEDICAL UNIVERSITY HOSPITAL
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DPC Image of A Volunteer
Knee joints
Confidential
Interface between a
cartilage and a
meniscus
Surface of a
cartilage
Interface between a
cartilage and a
meniscus
Surface of a
cartilage
SAITAMA MEDICAL UNIVERSITY HOSPITAL
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DPC Image of A patient
Knee joints
- Comparison with MRI -
Confidential
SAITAMA MEDICAL
UNIVERSITY HOSPITAL
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3 images of
Mastectomy Specimen
Confidential
IDC
NAGOYA MEDICAL CENTER
papilloma
FEA
ATT
DPC
ALH
SAS
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Confidential
Dynamic Chest X-Ray Imaging
ＪＳＴ（独立行政法人 科学技術振興機構）プロジェクト
System Configuration
Confidential
【Inside x-ray room】
FPD for dynamic image
■ Exposure condition
SID=2m
Upright Radiographic
stand
Pulsed X-ray
generator
【Outside x-ray room】
Exposure switch
ON
•X-ray photography is now in operation
using this X-ray equipment at a
collaborating research hospital .
Console PC
X-ray
generator
console
X-ray image acquisition(7.5fps)
Tube voltage：100kV
Filter：0.5mmAl+0.1mmCu
Tube current-time product：
0.1mAs/frame
Grid：80line/cm
Frame rate：7.5frame/second
Pixel size：194μm
Matrix size：1536x2048pixel
Examination time：10second
Entrance surface dose is three
to five times more than
a simple chest X-ray
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Extraction of Ventilation and
Perfusion Information
Confidential
Ventilation
Dynamic Image
☆Advantage of Dynamic Chest X-ray Examination
It is possible to extract both ventilation and perfusion information
using one original dynamic chest image.
Extraction of
low-frequency changes
Original Dynamic
Chest Image
(Normal)
Extraction of
ventilation information
Decrease
(White) Transit dose
Increase
(Black)
Perfusion
Dynamic Image
Extraction of
perfusion information
Extraction of
high-frequency changes
Decrease
(White)
Transit dose
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Ventilation Analysis Result
low
high
flow rate
Healthy Volunteer
Age 36
%VC
FEV1.0%
%FEV1
Confidential
large
small
Log(TFPI/TFPE)
Average
Male
-0.0589
S.D.
0.1603
Average
0.0755
S.D.
0.1679
Average
0.1485
S.D.
0.2057
Average
0.2110
S.D.
0.2122
Average
0.3488
S.D.
0.3146
130.8%
82.9%
104.8%
GOLD Ⅰ
Age 57
Female
%VC
114.5%
FEV1.0%
69.8%
%FEV1
84.4%
GOLD Ⅱ
Age 75
Male
%VC
86.3%
FEV1.0%
67.9%
%FEV1
62.2%
GOLD Ⅲ
Age 77
Male
%VC
98.3%
FEV1.0%
34.7%
%FEV1
40.8%
GOLD Ⅳ
Age 73
Male
%VC
55.5%
FEV1.0%
20.9%
%FEV1
11.8%
Result of spirometry
Original dynamic
image
TPFI
TPFE
MFRR
Histogram of MFRR
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Perfusion Analysis Result
Confidential
Pulmonary artery
phase image
Original
Dynamic Image
• Gender : Female
• Age : 77-year-old
• Disease :
Pulmonary embolism
• Field of blood flow decrease：
Right low lung field
Tc-99m MMA Perfusion
scintigraphpy image
Blood flow
decrease
small
correlation value
large
Contrast enhanced
CT image
Pulmonary artery
phase image
Original
Dynamic Image
• Gender : Female
• Age : 75-year-old
• Disease :
MAC disease
Interstitial pneumonia
• Field of blood flow decrease：
Right lung field
Blood flow
decrease
small
correlation value
large
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Confidential
Ultrasound TTHI
(Triad Tissue Harmonic Imaging)
ＪＳＴ（独立行政法人 科学技術振興機構）プロジェクト
Triad Tissue Harmonic Imaging (TTHI)
 Konica Minolta provides the high-definition image with combination of
wideband send/receive transmission image engine and image processing
for full image characteristics.
Confidential
Probe Technology
・Multi-Layer Acoustic Integration
Technology
・Minute Machining Technology
・Material Technology
HW Technology
・Frequency Range Expansion
・Lateral resolution improvement
・Range Resolution Improvement
Realization of
high-definition
image
SW Technology
・Triad Tissue Harmonic Imaging
(Image build with different tone/all chord including the
3rd harmonic band)
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High Quality Image #1
Confidential
MP Joint Flexor Tendon
Shoulder rotator cuff
Mammary gland Lymph node
Carotid artery
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High Quality Image #2
Confidential
Liver Hepatic vein
Liver Kidney
Abdominal Artery
Carotid Artery PWD/Color
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Visualization
Confidential
The super Needle visualization function is to project needle tips clearly
 The Function is to capture the needle tip visually with an emphasis by
Konica Minolta’s image processing technology which is not dependent
on the reflection intensity of the ultrasonic signal.
Needle tip signal serial
tracking technology
Probe
Position of Needle tip
Needle tip signal
alternative extraction
technique
Emphansis of needle tip
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