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PBMNC RNA DNA-BC DNA-G PBMNC - + + + + + + + + + + + + + + + + + + + + + + + + + + LTNP + + + NTH + + + SC + + Historic + + Hepatitis B + + + Hepatitis C + + + Bacteraemia* + + + SLE + + Healthy Controls + Hospital Controls + Sera + Urine RP Biopsy Plasma HIV Sequence data HIV Gag clones Open Access HLA type Types of samples archived HIV: HIV cBRC + + Cohorts HIV Proteinurea RA Needle biopsy RA (OPTTIRA) HIRD MS Evelena Samples in green are currently available, those in blue are ongoing collections. SC: seroconverters; SLE: systemic lupus erythematosus ; MS: multiple sclerosis; RA: rheumatoid arthritis; HIRD: human immune response dynamics study of immune changes following H1N1 vaccination. PBMNC: peripheral blood mononuclear cells. *Infections include those caused by: Bacteriods fragilis; Citrobacter koseri; Coliform bacteria;Escherechia coli; Enterobacter cloacae; Enterococcus faecalis; Gram -'ve rods;Group A streptococcus; Haemophilus influenza; Klebsiella species; Morganella morganii; Pneumonococcal meningitis;Propionibacterium; Proteus mirabilis; Pseudomonas aeruginosa; Serratia marcescens;Staphylococcus aureus; MR-Staphylococcus aureus; MS-Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus millen; Streptococcus oralis; Streptococcus pneumonia; Streptococcus pyogenes; Streptococcus salivasius; Streptococcus viridians;and, Streptococcus Group B Physical nature of the samples Plasma and Sera: 1ml aliquots stored at -80°C Urine: 1ml aliquots stored at -80C RNA: 1x10E7 viable PBMNC into 0.75ml QiazolTM stored at -80°C DNA-BC: 1 ml whole blood cell (wbc) pellet stored at -80°C DNA-G: 1 ml wbc after extraction of PBMNC stored at -80°C (n.b. ~200 ng DNA can be also be provided) PBMNC: 1x10E7 viable PBMNC/vial stored at in 90% serum/10% dimethyl-sulphoxide at -196°C