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The study presented in this thesis was conducted within the EMGO Institute for Health and Care Research (EMGO+), Department of General Practice & Elderly Care Medicine of the VU University Medical Center, Amsterdam, the Netherlands. The EMGO+ Institute participates in the Netherlands School of Primary Care Research (CaRe),whichhasbeenacknowledgedbytheRoyalDutchAcademy(KNAW). The study was funded by a grant from The Netherlands Organisation for Health ResearchandDevelopment(ZonMw),TheHague(grantnumber205100011). Financial support for the printing of this thesis was kindly provided by the VU University(Amsterdam). VanBuul,L.W. HowtoIMPACTantibioticprescribing? Acontributiontoantibioticstewardshipinlongtermcare ISBN: 9789462950955 Coverdesignandlayout: LauraW.vanBuul Printedby: Proefschriftmaken.nl||UitgeverijBOXPress Thebalanceonthecoverpicturerepresentstheweighingofthemanyconsiderations involvedinantibioticprescribingdecisionmaking.Onesideofthebalanceoutweighs theotherside,indicatingthatconsiderationsregardingantibioticprescribingarenot inbalance.Theanswertothequestion‘whyisthereimbalance?’canbefoundinthe conclusion of this thesis. The consequence of the imbalance is that antibiotics are becominginreachofresistantbacteria. ©2015,LauraW.vanBuul,Rotterdam,theNetherlands. All rights reserved. No part of this thesis may be reproduced or transmitted, in any formorbyanymeans,electronicormechanical,includingphotocopying,recordingor anyinformationstorageorretrievalsystem,withoutpriorpermissionofthecopyright owner.