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Dr Carsten Kröger
Short CV
Since 2015: Assistant Professor in Microbiology, Department of Microbiology,
Moyne Institute of Preventive Medicine, Trinity College Dublin
2014-2015: Postdoctoral researcher, Department of Functional and
Comparative Genomics, Institute of Integrative Biology, University of Liverpool
2010-2014: Postdoctoral researcher, Department of Microbiology, Moyne
Institute of Preventive Medicine, Trinity College Dublin
2006-2014: Dr. rer. nat (PhD), Technische Universität München, ZIEL Research
Center for Nutrition and Food Sciences, Wissenschaftszentrum Weihenstephan,
Germany
Research – Functional Genomics of Bacterial Pathogens
Our research focusses on virulence gene regulation, antibiotic resistance and RNA biology of Gramnegative bacterial pathogens using Salmonella enterica and Acinetobacter baumannii as model
organisms. To adapt and respond to changing conditions during infection and in the environment,
bacteria possess the remarkable ability to modulate their gene expression programs quickly and
efficiently. We use whole genome (Next-Generation Sequencing, RNA-seq) and gene specific methods to
study transcriptional networks, mechanisms and antibiotic resistance of Gram-negative pathogens and
their regulation (by small RNAs and protein transcription factors) to understand how bacterial
pathogens sense, respond and survive during environmental changes.
Selected Publications:
RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium
Srikumar S*, Kröger C et al. PLoS Pathogens 2015 Nov 12;11(11):e1005262. *Contributed equally
An infection-relevant transcriptomic compendium for Salmonella enterica serovar Typhimurium.
Kröger C et al. Cell Host Microbe. 2013 Dec 11;14(6):683-95.
The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium.
Kröger C et al. Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1277-86.
Bistability in myo-inositol utilization by Salmonella enterica serovar Typhimurium.
Kröger C*, Srikumar S* et al. J Bacteriol. 2011 Mar;193(6):1427-35. *contributed equally
Characterization of the myo-inositol utilization island of Salmonella enterica serovar Typhimurium.
Kröger C, Fuchs TM. J Bacteriol. 2009 Jan;191(2):545-54.
Contact:
Email: [email protected]
Telephone: +353 1 896 1414
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