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Dr Carsten Kröger Short CV Since 2015: Assistant Professor in Microbiology, Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin 2014-2015: Postdoctoral researcher, Department of Functional and Comparative Genomics, Institute of Integrative Biology, University of Liverpool 2010-2014: Postdoctoral researcher, Department of Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin 2006-2014: Dr. rer. nat (PhD), Technische Universität München, ZIEL Research Center for Nutrition and Food Sciences, Wissenschaftszentrum Weihenstephan, Germany Research – Functional Genomics of Bacterial Pathogens Our research focusses on virulence gene regulation, antibiotic resistance and RNA biology of Gramnegative bacterial pathogens using Salmonella enterica and Acinetobacter baumannii as model organisms. To adapt and respond to changing conditions during infection and in the environment, bacteria possess the remarkable ability to modulate their gene expression programs quickly and efficiently. We use whole genome (Next-Generation Sequencing, RNA-seq) and gene specific methods to study transcriptional networks, mechanisms and antibiotic resistance of Gram-negative pathogens and their regulation (by small RNAs and protein transcription factors) to understand how bacterial pathogens sense, respond and survive during environmental changes. Selected Publications: RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium Srikumar S*, Kröger C et al. PLoS Pathogens 2015 Nov 12;11(11):e1005262. *Contributed equally An infection-relevant transcriptomic compendium for Salmonella enterica serovar Typhimurium. Kröger C et al. Cell Host Microbe. 2013 Dec 11;14(6):683-95. The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium. Kröger C et al. Proc Natl Acad Sci U S A. 2012 May 15;109(20):E1277-86. Bistability in myo-inositol utilization by Salmonella enterica serovar Typhimurium. Kröger C*, Srikumar S* et al. J Bacteriol. 2011 Mar;193(6):1427-35. *contributed equally Characterization of the myo-inositol utilization island of Salmonella enterica serovar Typhimurium. Kröger C, Fuchs TM. J Bacteriol. 2009 Jan;191(2):545-54. Contact: Email: [email protected] Telephone: +353 1 896 1414