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Gene Regulation
Prokaryotes
(no nucleus)
Lac operon
• System of genes that can turn on and off
in E. coli (bacteria).
• These genes make enzymes that break
down the sugar in milk (lactose).
• Regulatory genes~ genes that affect other
genes (make them turn on or off)
• Structural genes~genes that code for a
protein
Structure of the Lac operon
Regulatory genes
S g #3
S g #2
Inhibitor/repressor (gene)
Promoter “region” (gene)
Operator “region” (gene)
Structural gene #1
Function of the Lac operon
Regulatory genes
S g #3
S g #2
Inhibitor/repressor (gene)
Promoter “region” (gene)
Operator “region” (gene)
Structural gene #1
Proteins that break down lactose
Repressor
(protein)
inhibitor
?
promoter
Lactose
operator
SG 1
SG2
RNA
polymerase
SG3
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