Download Spersanicol®

Spersanicol®
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Generic name :
Chloroamphenicol
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Trade name:
Spersanicol ®
Spersanicol®
Properties and effect:
 chloroamphenicol is low molecular ,
primarily lipophilic antibiotic which is
active against gram- positive and
gram- negative bacteria such as
salmonella and chlamydiae .
 It has been show to act impairing bacterial
protein synthesis .
Spersanicol®
 Indication:
Bacterial infection of the anterior portion of
eye lids and tear duct.
 Infection prophylaxis pre- and
postoperatively, after chemical or other
burn.
 Trachoma, herpes zoster opthalmicus.
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Spersanicol®
Dosage/ use:
 Eye drops:
Instill1 drop 2-4 times daily in the
conjunctival sac.
Acute case: up to 1 drop every hour
 Ointment:
Apply a 3-5 strip of ointment 2-4 times daily
into the into the lower conjunctival sac .
acute case: every 2 hour.
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Spersanicol®
Adverse reaction:
 Rare allergic reaction (eczema of the lid
margins)
 Following long term topical (2-3 month)
with chloroamphenicol ,aplastic anemia
has occasionally been observed
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Spersanicol®
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Drug Interaction:
Spersanicol should not be administered
concurrently with bactericidal substance
(penicillin ,cephalosporin ,gentamicin ,
tetracycline ,vancomycin ) or in
conjunction with systemic treatment with
drug affecting hematopoisis ,sulfonylureas
,coumarin derivative hydantoin or
methotrexate.
Spersanicol®
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Stability:
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Store eye drop in refriergerator (2-8°C).
Close bottle and tube immediately after use .
Once opened ,the eye drops should not be
kept longer than one month.
Any medication left over after completion of
treatment should be discarded.
If unopened , Spersanicol eye drops and
ointment can be used until the expiry date on
the package.
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