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Concepts of Genetics
Ninth Edition
Klug, Cummings, Spencer, Palladino
Chapter 11
DNA Replication
and Recombination
Copyright
© 2009©Pearson
Education,
Inc.
Copyright
2009 Pearson
Education,
Inc.
11.1
DNA Is Reproduced by
Semiconservative Replication
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.1
Copyright © 2009 Pearson Education, Inc.
Figure 11.2
11.1
DNA Is Reproduced by
Semiconservative Replication
11.1.1
The Meselson–Stahl Experiment
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.3
Copyright © 2009 Pearson Education, Inc.
Figure 11.4
11.1
DNA Is Reproduced by
Semiconservative Replication
11.1.2
Semiconservative Replication in Eukaryotes
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.5
Copyright © 2009 Pearson Education, Inc.
Figure 11.5a
Copyright © 2009 Pearson Education, Inc.
Figure 11.5b
Copyright © 2009 Pearson Education, Inc.
Figure 11.5c
11.1
DNA Is Reproduced by
Semiconservative Replication
11.1.3
Origins, Forks, and Units of Replication
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.6
11.2
DNA Synthesis in Bacteria Involves
Five Polymerases, as well as Other
Enzymes
11.2.1
DNA Polymerase I
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.7
Copyright © 2009 Pearson Education, Inc.
Figure 11.8
Copyright © 2009 Pearson Education, Inc.
Table 11.1
11.2
DNA Synthesis in Bacteria Involves
Five Polymerases, as well as Other
Enzymes
11.2.2
11.2.3
Synthesis of Biologically Active DNA
DNA Polymerase II, III, IV, and V
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 11.2
Copyright © 2009 Pearson Education, Inc.
Table 11.3
11.3
Many Complex Tasks Must Be
Performed during DNA Replication
11.3.1
Unwinding the DNA Helix
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.9
11.3
Many Complex Tasks Must Be
Performed during DNA Replication
11.3.2
Initiation of DNA Synthesis With an RNA
Primer
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.10
11.3
Many Complex Tasks Must Be
Performed during DNA Replication
11.3.3
Continuous and Discontinuous DNA Synthesis
of Antiparallel Strands
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.11
11.3
Many Complex Tasks Must Be
Performed during DNA Replication
11.3.4
Concurrent Synthesis Occurs on the Leading
and Lagging Strands
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.12
11.3
Many Complex Tasks Must Be
Performed during DNA Replication
11.3.5
Integrated Proofreading and Error Correction
Copyright © 2009 Pearson Education, Inc.
11.4
A Summary of DNA Replication in
Prokaryotes
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.13
11.5
Replication in Prokaryotes Is
Controlled by a Variety of Genes
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 11.4
11.6
Eukaryotic DNA Synthesis Is Similar
to Synthesis in Prokaryotes, but More
Complex
11.6.1
Multiple Replication Origins
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.14
Copyright © 2009 Pearson Education, Inc.
Figure 11.15
11.6
Eukaryotic DNA Synthesis Is Similar
to Synthesis in Prokaryotes, but More
Complex
11.6.2
Eukaryotic DNA Polymerases
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Table 11.5
11.7
Telomeres Provide Structural Integrity
at Chromosome Ends but Are
Problematic to Replicate
11.7.1
11.7.2
Telomere Structure
Replication at the Telomere
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Figure 11.16
Copyright © 2009 Pearson Education, Inc.
Figure 11.17
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