Download Microbiology of the GIT

Microbiology of the GIT
Ziad Elnasser, MD, Ph.D
Introduction
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Food borne illnesses.
Acute diarrhea, vomitting (food poisoning)
Non food causes.
GIT as a vehicle only.
Fecal oral mode.
Toxins of Microorganisms.
■ Enterotoxins.
■ Cytotoxins.
■ Neurotoxins.
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Normal flora, bowel motility, immunity.
Types of foods associated with various pathogens that cause food poisoning.
TYPES OF FOODS ASSOCIATED WITH VARIOUS PATHOGENS THAT CAUSE FOOD POISONING
Pathogen
Foods
Staphylococcus aureus
Cream pastries, salads, meat products, cold foods
Bacillus cereus
Fried rice, vegetables, meat dishes, vanilla sauce
Clostridium perfringens
Cooked meats, gravies
Vibrio cholerae, Vibrio parahaemolyticus,
Vibrio vulnificus
Shellfish, seafood
Campylobacter jejuni
Milk, poultry
Salmonella enteritidis
Eggs, poultry, other meats
Shigella spp.
Salads, milk, cold foods
Yersinia enterocolitica
Milk, pork products
Escherichia coli
Ground beef, milk, lettuce, unpasteurized cider
Listeria monocytogenes
Soft cheese, paté, milk, coleslaw
Clostridium botulinum
Meats, home-canned fruit and vegetables
Hepatitis A and enteric viruses
Shellfish, various foods
Micro-organisms associated with water-borne infections.
MICRO-ORGANISMS ASSOCIATED WITH WATER-BORNE INFECTIONS
Bacteria
Vibrio cholerae
Vibrio parahaemolyticus
Campylobacter jejuni
Shigella spp.
Escherichia coli (especially enterotoxigenic Escherichia coli)
Viruses
Rotavirus
Norwalk virus
Small round-structured viruses
Hepatitis A virus
Hepatitis E virus
Protozoa
Giardia lamblia
Entamoeba histolytica
Cryptosporidium parvum
Isospora belli
Cyclospora cayetanensis
Microsporidia spp.
Dientamoeba fragilis
Balantidium coli
Enterobacteriacae
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General properties.
O, K, and H antigens.
Toxins.
Apportunistic infections.
Intestinal infections: Salmonella, Shigella,
Yersinia enterocolitica, and certain E. coli.
Dysentry, watery diarrhea, and Enteric fever.
Pathogenesis, Immunity, Diagnosis, and
Treatment.
E. Coli intestinal infections
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Based on their virulence properties.
ETEC.
 EPEC.
 EIEC.
 EHEC.
 EAEC.
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Shigella
General properties.
 Classification.
 Epidemiology.
 Pathogenesis.
 Clinical presentation.
 Diagnosis.
 Treatment.
 Prevention.
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Salmonella
Bacteriology.
 Epidemiology
 Pathogenesis.
 Immunity.
 Typhoid fever.
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Yersinia
Bacteriology
 Epidemiology
 Pathogenesis
 Clinical manifestations
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