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Digestion, Absorption, and Transport Chapter 3 Whitney & Rolfes – Understanding Nutrition, 12th Edition Digestion Breaking down foods into nutrients Prepare for absorption Challenges of digestion Tasks of the mouth Diaphragm Steady movement Lubrication of food Digestive enzyme functions Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Gastrointestinal (GI) tract Flexible and muscular Path Mouth → esophagus → stomach → small intestine → large intestine → rectum → anus Lumen Continuous Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Mouth Process of digestion begins Mastication Four basic taste sensations Savory Aroma, texture, and temperature Pharynx Bolus Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Esophagus Two sphincters Upper esophageal sphincter Lower esophageal sphincter Stomach Movement of bolus Chyme Pyloric sphincter Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Small intestine Common bile duct Pancreas and gall bladder Three segments Large intestine (colon) Ileocecal valve Withdrawal of water Rectum and anus Whitney & Rolfes – Understanding Nutrition, 12th Edition Anatomy of the Digestive Tract Whitney & Rolfes – Understanding Nutrition, 12th Edition Transverse colon Opening from small intestine to large intestine Ascending colon End of small intestine Appendix Descending colon Rectum Anus Sigmoid colon Stepped Art Fig. 3-2, p. 72 Muscular Action of Digestion Peristalsis Circular and longitudinal muscles working together Rate and intensity of contractions vary Factors that may interfere with peristalsis Stomach action Circular, longitudinal, and diagonal muscles Timing the release of chyme Whitney & Rolfes – Understanding Nutrition, 12th Edition Muscular Action of Digestion Whitney & Rolfes – Understanding Nutrition, 12th Edition Muscular Action of Digestion Segmentation Contraction of circular muscles in small intestine Mix chyme Promote contact with absorption cells Sphincter contractions Periodically open and close Control pace of GI tract contents Whitney & Rolfes – Understanding Nutrition, 12th Edition Muscular Action of Digestion Whitney & Rolfes – Understanding Nutrition, 12th Edition Muscular Action of Digestion Whitney & Rolfes – Understanding Nutrition, 12th Edition Secretions of Digestion Five organs Salivary glands, stomach, pancreas, liver, small intestine Secretions Water Enzymes Protein facilitator of chemical reactions Hydrolysis Whitney & Rolfes – Understanding Nutrition, 12th Edition Secretions of Digestion Saliva Moisten food for easy passage Protective role Carbohydrate digestion Gastric juice Protein digestion Mucus pH units Whitney & Rolfes – Understanding Nutrition, 12th Edition Secretions of Digestion Pancreatic juice Released via ducts into duodenum Enzymes act on all three energy nutrients Sodium bicarbonate Bile Liver Gallbladder Whitney & Rolfes – Understanding Nutrition, 12th Edition Secretions of Digestion Whitney & Rolfes – Understanding Nutrition, 12th Edition The Final Stage Vitamin and mineral absorption Undigested residues Exercise intestinal muscles Retention of water Colon Intestinal bacteria Recyclable materials Water and dissolved salts Whitney & Rolfes – Understanding Nutrition, 12th Edition Whitney & Rolfes – Understanding Nutrition, 12th Edition Absorption Small intestine Majority of absorption Ten feet long Surface area Absorption techniques Simple diffusion Facilitated diffusion Active transport Whitney & Rolfes – Understanding Nutrition, 12th Edition Absorption Whitney & Rolfes – Understanding Nutrition, 12th Edition Carrier loads nutrient on outside of cell . . . Outside cell Carrier loads nutrient on outside of cell . . . Cell membrane Inside cell . . . and then releases it on inside of cell. SIMPLE DIFFUSION Some nutrients (such as water and small lipids) are absorbed by simple diffusion. They cross into intestinal cells freely. FACILITATED DIFFUSION Some nutrients (such as the watersoluble vitamins) are absorbed by facilitated diffusion. They need a specific carrier to transport them from one side of the cell membrane to the other. (Alternatively, facilitated diffusion may occur when the carrier changes the cell membrane in such a way that the nutrients can pass through.) . . . and then releases it on inside of cell. ACTIVE TRANSPORT Some nutrients (such as glucose and amino acids) must be absorbed actively. These nutrients move against a concentration gradient, which requires energy. Stepped Art Fig. 3-9, p. 78 Anatomy of the Absorptive System Villi Select and regulate nutrients absorbed Microvilli Enzymes and “pumps” Crypts Secretion of intestinal juices Goblet cells Mucus secretion Whitney & Rolfes – Understanding Nutrition, 12th Edition Whitney & Rolfes – Understanding Nutrition, 12th Edition Preparing Nutrients for Transport Transport pathways Bloodstream Water-soluble nutrients and smaller products of fat digestion Liver Lymphatic system Larger fats and fat-soluble vitamins Chylomicrons Bypass liver at first Whitney & Rolfes – Understanding Nutrition, 12th Edition The Vascular System Closed system of vessels Heart pump Blood Delivers oxygen and nutrients Removes carbon dioxide and wastes Blood flow Special routing for digestive system Liver Whitney & Rolfes – Understanding Nutrition, 12th Edition The Vascular System Whitney & Rolfes – Understanding Nutrition, 12th Edition The Vascular System Whitney & Rolfes – Understanding Nutrition, 12th Edition The Lymphatic System One-way route No pump Circulation between cells Entry into bloodstream Subclavian vein Nutrients in lymphatic vessels Bypass liver at first Whitney & Rolfes – Understanding Nutrition, 12th Edition Health and Regulation of GI Tract Gastrointestinal bacteria – flora Most are not harmful Benefits of gastrointestinal bacteria Factors influencing bacteria presence Diet – probiotics Others Digestion of fibers and complex proteins Vitamin production Whitney & Rolfes – Understanding Nutrition, 12th Edition Health and Regulation of GI Tract Endocrine and nervous systems Homeostatic regulation Hormones and nerve pathways Stimulation and inhibition of digestive secretions Feedback mechanisms Examples GI hormones Whitney & Rolfes – Understanding Nutrition, 12th Edition Health and Regulation of GI Tract Whitney & Rolfes – Understanding Nutrition, 12th Edition Health and Regulation of GI Tract Whitney & Rolfes – Understanding Nutrition, 12th Edition The Digestive System at Its Best Sensitive and responsive to environment Immunity against intestinal diseases Defense against foreign invaders Health of digestive system Healthy supply of blood Lifestyle factors Types of foods eaten Balance, moderation, adequacy, and variety Whitney & Rolfes – Understanding Nutrition, 12th Edition Highlight 3 Common Digestive Problems Whitney & Rolfes – Understanding Nutrition, 12th Edition Choking Food slips into trachea Cuts off breathing International sign for choking Heimlich maneuver Foods commonly associated with choking Prevention of choking Whitney & Rolfes – Understanding Nutrition, 12th Edition Choking Whitney & Rolfes – Understanding Nutrition, 12th Edition Choking Whitney & Rolfes – Understanding Nutrition, 12th Edition Vomiting and Diarrhea Vomiting Adaptive mechanism of the body Medical treatment Dehydration and projectile vomiting Diarrhea Symptom of medical conditions & treatments Irritable bowel syndrome (IBS) Colitis Treatment Whitney & Rolfes – Understanding Nutrition, 12th Edition Constipation Not a disease Symptoms of constipation Causes Lifestyle Side effect of medications Prevention Fiber and water Physical activity Whitney & Rolfes – Understanding Nutrition, 12th Edition Belching and Gas Belching Swallowed air Prevention Intestinal gas Consumption of certain foods Individually determined Hiccups Whitney & Rolfes – Understanding Nutrition, 12th Edition Heartburn and “Acid Indigestion” Gastroesophageal reflux (heartburn) Causes Prevention Indigestion Causes Antacids and acid controllers Damage to esophagus Barrett’s esophagus Whitney & Rolfes – Understanding Nutrition, 12th Edition Ulcers Peptic ulcers Gastric ulcers Duodenal ulcers Causes Bacterial infection Anti-inflammatory drugs Excessive gastric acid secretion Ulcer treatment regimen Whitney & Rolfes – Understanding Nutrition, 12th Edition Whitney & Rolfes – Understanding Nutrition, 12th Edition