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CHEE 450 Design Project:
Air Filtration
Kelsea Fitzpatrick | Kristen DeJong | Kelsey Barton
Presentation Outline
 Introduction and Design Considerations
 Aerosols
 HEPA Filters
 Filtration Mechanisms
 Proposed Design
 Alternatives
Introduction and Design
Considerations
 Air filter is initial step in insulin process, sterilizing
fermentor feed
 SuperPRO output:
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Fermentation as batch process
Feed composition of ammonia, nitrogen, and oxygen
Unspecified particulate matter
1166 m3/hr average flowrate
 Sterilized air required for fermentor to ensure no batch
contamination
Aerosols
 Solid and liquid contaminants suspended in gas streams
 Typical size: 0.001 µm to 100 µm
 Particulates follow lognormal distribution
 Examples: Soil, bacteria, pollen…
Soil Particles (magnified)
E. coli bacteria
Pollen Particles (magnified)
Vacuum cleaner HEPA filter
HEPA Filters
 High Efficiency Particulate Filter
 Removes at least 99.97% of air borne particles > 0.3 µm
 Requires prefilter system to capture larger particles
 Initially developed in 1940’s for a top-secret method of
eliminating radioactive particulate
 Currently used in: electronic, medical, pharmaceutical,
and nuclear fields
Filtration Mechanisms
Proposed Design
 Recommended filters from Cambridge Filter Corp
 Prefilter
 Aero-Answer Mate - $75.00
 60-65% efficiency
 1580 m3/h
 HEPA Filter
 Absolute Filter - $160.00
 99.97% efficiency
 1680 m3/h
 Considerations
 Moisture susceptibility
 Replacement cost and frequency
Ozone molecule
Alternatives
 Air filtration alternatives
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
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Ozone (O3) injection
UV Radiation
Gas Scrubbing
Heat
 Serves to kill biological particles but not necessarily
remove all physical or chemical particles
 Less economical