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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this site. Copyright 2012, The Johns Hopkins University and James D. Yager. All rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided “AS IS”; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as needed. Section B Cancer Where Does It Occur? What Is It? 18 http://info.cancerresearchuk.org/cancerstats/world/ 19 Cancer What is it? – Group of diseases – Uncontrolled growth – Spread (invasion, metastasis) – Multiyear process 24 Key Points – Section B Rising cancer incidence is a global problem US cancer incidence and death rates for a number of cancer sites is declining Cancer is a group of diseases characterized by uncontrolled growth and progression from pre-cancer to invasive, malignant cancer Development of a malignant tumor can take 10-20 years making attribution of cause to effect difficult Continued 25