Download No Slide Title

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Document related concepts
no text concepts found
Transcript
Health Psychology
Chapter 10: Cancer
Spring 2000
Mansfield University
Dr. Craig, Instructor
1
Cancer Facts and Terms
 In 1997 was the 2nd leading cause of death


201/100,000 population
40-60% of premature deaths due to life and
environmental factors
 Cancer- new cells that grow out of control and
can affect other healthy organismic functioning.


tumors
Can affects all cell-based creatures
 Mutation- change in cell function

can be generated by external agents (x-ray,
benzene, asbestos)
Cancer Terms continued
 Mutated Cells: “neoplastic cells”

cause autonomous“neoplastic growth” that robs
organism of nutrients (provides no benefit).
 Benign cells
localized growth
 Malignant cells
“metastasize”, that is spread and setup new
colonies.

Typically through blood or lymphatic system.
Types of Cancer
 Carcinomas- cancer of cells that provide outer and inner
lining to the body




stomach, skin, lung
85% of cancers
risk increase with age
Carcinogens- substances increase rate of carcinomas
 Sarcomas- cancers of connective tissue


bone, muscle
2% of cancers
 Leukemia- blood or blood forming cells

stem cells in the bone marrow (make immune cells)
 Lymphoma- cancer of lymphatic system

relatively rare
Changes in Cancer Mortality Statistics
 Cancer death 3x greater now than in 1900





Why?
1. More accurate techniques for diagnosis
2. Some decline in CV mortality (live longer)
3. Rapid rise of AIDS-related cancer deaths
4. Sharp increase in lung cancer tied to cigarette
smoking
Variations in Cancer Mortality
 All-Cancer mortality dropping since 1950 for men
and women across all ages (Fig. 10.2 & 3)
 Lung Cancers- curve rising for women (10.5),
high, but recent decrease for men (10.4).
 Major sites for Men:

lung, prostate, colo-rectal, pancreas
 Major site for Women:



lung, breast, colo-rectal, pancreas
breast cancer 5 year survival improved, but little change in
total mortality statistics
colo-rectal rates declining for women, but not men.
Behavioral Risk Factors for Cancer
 Smoking
• account for 400,000 deaths annually (including other
than deaths)
• the leading cause of cancer deaths
• 9x increase risk of cancer death (strongest single factor
in behavioral science)
 Dose-response relationship between cancer risk
and cigarettes smoked
 15-25 year lag in mortality statistics
• faster declines in smoking among men 25-years ago,
equates to more drastic decrease in LC mortality now.
 Breast Cancer- Dose-response relationship but increased
risk not as great as LC (75% for those 40 or more cigs/day)
Smoking Continued
 Synergistic effects with environmental factors

pollution, SES, occupation, ethnicity, building
materials
 ETC...

Optimistic Bias- “recognize problem exist for
everyone else... but not me”
• clear in HS students
• heavy smokers

Pipe and Cigars- 2.5 and 2.9x increase in cancer
rates respectively. Combine with cigarettes 8.1 and
6.9 increase risk!!!
Potential BRF: Diet
 Estimated that 1/3 of cancers may be related to
dietary choices

(Fats- bad, F & Vegs- Good)
 Bad Foods?
• spoiled foods
• weight gain after 18 years old
• proteins and non-vegetable fats


50% of cals from fat = 3x risk of breast cancer
high cholesterol level- 2x risk of LC in men
 Good Food
• Vit. A & beta-carotene (carrots, sweet potatoes) (weak)
• Pizza (lycopene)- cooked tomatoes
• Vit. C- (ascorbic acid)- inhibits carcinogen nitrosamine
BRF: Alcohol, Physical Activity
 Alcohol- potential secondary RF
• little evidence in the way of direct causal relationship
• set stage for weakened response (cirrhotic liver)
• synergistic effects with smoking
 Physical Activity (or inactivity)
• Breast Cancer

50% less in women who began exercising regularly in early life
(by early adulthood ?)
less in women who exercise at least 4 hrs weekly (particularly in
pre-menopausal women)
• Prostate Cancer


low activity jobs/sendentary behavior raises risk in later
life
regular exercise markedly reduces risk
• Colon Cancer- “jury is still out”
BRF: Exposure to UV Light, Sexual Behavior
 Skin Cancer• particularly a problem with fair-skinned people, light hair,
blue eyes
• risk of exposure greatest among young
 Why is it not taken more seriously?

Low threat of mortality
 Sexual Behavior
• cancers resulting form AIDS

Kaposi’s Sarcoma- purple nodules with skin lesions (internal
and external) more likely in gay men than other AIDS patients
• Cervical Cancer

early partnering, multiple partnering, hygiene, not using barrier
forms of contraception
protection appears offered by childbirth early in life
RF over which we have little control
 Environment

radiation, asbestos, pesticides, chemicals
 Nuclear Power plants- long term exposure to work environment
appear to increase many chronic forms of mortality, including cancer.

living in the vicinity of a power plant does not!!

Study of 40 million people over 35 years
 High Power Lines
• NO EVIDENCE after many good studies-- a myth
 Inherent Risk Factors


most cancers are not heritable
FH of Cancer
• breast cancer risk is 2-3x greater
Inherent Risk Factors
 Ethnic Background


40-50% greater incidence in AA than Eur. A
EA greater than Asian, Native Americans
• believed to be related to social/behavior factors not
genetic structure

SES, knowledge about cancer and its treatment, attitudes
toward disease (optimistic bias), access to good health
care.
 Age


see figure 10.6
steep increase after 45 years especially for men.
Psychological Factors and Cancer
 The “Type C” Personality

no global personality trait linked to cancer.. However…
 Suppression of Emotion



suppression of emotion, denial of anger significantly
increased changes of breast cancer 5-years follow-up after
biopsy (Greer & Morris)
MMPI measured suppression predicted male-cancer
diagnosis 10 years later
Physicians who suppressed and were “loners” were 16x
more likely to have cancer in a 30 year follow-up!
 Depression

a RF for dying of cancer, but not contracting it.
Psychosocial Factors and Survival
 Key Variables:

“Fighting spirit”, Marriage/social support, Therapy
 Be a fighter


better adjusted, less hostile, less angry... More likely to die
why do you think?
 Married people seems to survive longer



why? (they’re diagnosed earlier.. explains a little)
social support appears to enhance personal control and
healthy behaviors, reduce optimistic bias?)
Speigel- breast cancer and supportive group psychotherapy
(video clip)