Download Achondroplasia Dwarfism

By: Trey A
WHAT IS THE GENETIC CAUSE OF
DWARFISM?
Is a mutation of the FGFR3 gene located on chromosome 4
 IS IT MORE COMMON IN MALE OF
FEMALE?
Dwarfism affects both male and female but it is found
more common in males.
IS IT MORE COMMON IN CERTAIN
ETHNIC GROUPS?
 IT IS MOSTLY FOUND IN CAUCASIAN BUT IS
SOMETIMES RARLY FOUND IN AFRICAN
AMERICANS
HOW OFTEN DOES THIS DISORDER OCCURE?

IF ONE PARENT HAS IT IT’S A 50% CHANCE THAT THE KID WILL GET IT. IF
BOTH PARENTS HAVE IT IT’S A 50% CHANCE THAT ONE WILL GET IT A 25%
CHANCE THAT THE KID WILL BE NORMAL AND 25% CHANCE THE KID WILL JUST
BE A LITTLE SHORTER THEN NORMAL BUT NOT DWARFED. 10 in 10000 babies
IS IT SEX LINKED OR AUTOSOMAL?

It is autosomal.
 IS IT DOMINANT OR RECESSIVE?

It is DOMINANT.
WHAT ARE THE SYMPTOMS OF THIS DISORDER?
 It makes people abnormally short. Can cause early arthritis
It can grind there bones and put them in a wheel-chair
uneven distribution of there weight

because the
CAN IT BE PERDICTED AT BIRTH?
It cant be predicted before birth but shortly after the kid is born they will
normally develop small bumps.