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Genetics
&
The Work of Mendel
Regents Biology
2007-2008
Gregor Mendel
 Modern genetics began in the mid1800s in an abbey garden, where a
monk named Gregor Mendel
documented inheritance in peas
used good experimental design
 used mathematical analysis

 collected data & counted them

excellent example of scientific
method
Regents Biology
Mendel’s work
Pollen transferred from white
flower to stigma of purple flower
 Bred pea plants
cross-pollinate
true breeding parents
 raised seed & then
observed traits
 allowed offspring
to self-pollinate
& observed next
generation

all purple flowers result
self-pollinate
Regents Biology
?
Mendel collected data for 7 pea traits
Regents Biology
Looking closer at Mendel’s work
Parents
P
true-breeding
true-breeding
X
purple-flower peas
white-flower peas
100%
purple-flower peas
1st = F1
generation
(hybrids)
100%
self-pollinate
2nd = F2
75%
purple-flower peas
generation
Regents Biology
25%
white-flower peas
3:1
What did Mendel’s findings mean?
 Some traits mask others

purple & white flower colors are
separate traits that do not blend
I’ll speak for
both of us!
 purple x white ≠ light purple
 purple masked white

dominant allele
 functional protein
 affects characteristic
 masks other alleles

recessive allele
 no noticeable effect
 allele makes a
Regents Biology
non-functioning protein
allele producing
functional protein
mutant allele
malfunctioning
protein
homologous
chromosomes
Genotype vs. phenotype
 Difference between how an organism
“looks” & its genetics

phenotype
 description of an organism’s trait

genotype
 description of an organism’s genetic
makeup
X
P
Explain Mendel’s results using
…dominant & recessive
…phenotype & genotype
Regents Biology
purple
white
F1
all purple
Making crosses
 Can represent alleles as letters
flower color alleles  P or p
 true-breeding purple-flower peas  PP
 true-breeding white-flower peas  pp

PP x pp
X
P
purple
white
F1
Regents Biology
all purple
Pp
Law of Segregation
 When gametes are formed, each
gamete carries only 1 copy of the gene
(allele)
Gametes are haploid!
egg
Zygote
sperm
Regents Biology
Punnett squares
 Pp x
1st
Pp
generation
(hybrids)
%
genotype
male / sperm
P
female / eggs
Aaaaah,
phenotype & genotype
can have different
ratios
p
PP
Pp
P
PP
Pp
p
Pp
pp
Regents Biology
%
phenotype
25%
75%
50%
Pp
pp
25% 25%
1:2:1
3:1
Any Questions??
Regents Biology
2007-2008
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