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caFE Server
Siteman Cancer Center
Introduction
 Annotate probes on microarrays using publicly available
biomedical databases
 Automatically update annotations on a regular basis
 Web-based and API based query search
 Uses caCORE SDK (version 1.0.3) generated code
 Working towards caGRID compliance
Data Sources
 Entrez Gene
 UniGene
 Gene Ontology
 dbSNP
 UniSTS
 HomoloGene
 PubMed
Annotation Interlinks
Microarrays
caArray
Custom
Entrez Gene
UniGene
GenBank
Gene ID
UniGene ClusterID
Accession Number
HomoloGene
dbSNP
PubMed
Gene Ontology
Orthologus genes
RefSNP ID
Pubmed relationship
GO terms
Limitations
 Initial run of PubMed data curation takes 2-3
months
 APIs generated using caCORE SDK


Not optimized for complex searches
Performing searches that involves complex
computations.

For example, searching for literature correlation
with depth 2 or more
 Meta-information of caArray is not stored
Demo
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