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Genetics Gregor Mendel: Father of Genetics Genetics: study of heredity Heredity: passing traits from parent to offspring Used peas to study heredity Why Peas? 1. Several Traits 2. Control mating 3. Small, grow easily, and matures quickly Alleles: Different versions of a gene Ex: White and Purple Flowers Mendel’s Experiment Monohybrid Cross: One pair of contrasting traits. Ex: Mating a plant with purple flowers with white flowers True-breeding: All offspring would have only one form of the trait Ex: Purple-flowering plant only has purpleflowered offspring Mendel’s Experiments Vocabulary Dominant: Expressed in appearance (A) Recessive: Not noticeable in appearance (a) Homozygous: AA or aa Heterozygous: Aa More Vocabulary Genotype: Genetic make up (ex: Pp) Phenotype: Appearance (ex: Purple flowers) Laws of Heredity Law of Segregation The two alleles for a trait separate when gametes are formed Law of Independent Assortment Alleles of different genes separate independently of each other during meiosis Law of Segregation Separation of alleles into separate gametes 50% chance that one allele will go into a gamete Law of Independent Assortment Punnett Square Ratios Test Cross Dihybrid Cross: Cross that involve two traits Incomplete Dominance and Codominance 17 Incomplete Dominance F1 hybrids have an appearance somewhat in between the phenotypes of the two parental varieties. Example: snapdragons (flower) red (RR) x white (rr) r r RR = red flower R rr = white flower R 18 Incomplete Dominance r r R Rr Rr R Rr Rr produces the F1 generation All Rr = pink (heterozygous pink) 19 Incomplete Dominance 20 Codominance Two alleles are expressed (multiple alleles) in heterozygous individuals. Example: blood type 1. 2. 3. 4. type A type B type AB type O = = = = IAIA or IAi IBIB or IBi IAIB ii 21 Codominance Problem Example:homozygous male Type B (IBIB) x heterozygous female Type A (IAi) IA i IB IAIB IBi IB IAIB IBi 1/2 = IAIB 1/2 = IBi 22 Another Codominance Problem • Example: male Type O (ii) x female type AB (IAIB) IA IB i IAi IBi i IAi IBi 1/2 = IAi 1/2 = IBi 23 Sex-linked Traits Traits (genes) located on the sex chromosomes Sex chromosomes are X and Y XX genotype for females XY genotype for males Many sex-linked traits carried on X chromosome 24 Sex-linked Traits Example: Eye color in fruit flies Sex Chromosomes fruit fly eye color XX chromosome - female Xy chromosome - male 25 Sex-linked Trait Problem Example: Eye color in fruit flies (red-eyed male) x (white-eyed female) XR Y x XrXr Remember: the Y chromosome in males does not carry traits. RR = red eyed Xr Xr Rr = red eyed rr = white eyed XY = male XR XX = female Y 26 Sex-linked Trait Solution: Xr XR XR Xr Y Xr Y Xr XR Xr Xr Y 50% red eyed female 50% white eyed male 27 Female Carriers 28