Download Supplementary Table S7 (ppt 134K)

Suraneni et al, table S7: Representative genes commonly upregulated in young transgenic
(fl26y and svb9y) and old wt (wto) VPs compared to young wt (wty) VPs
wto(vs)wty
fl26y(vs)wty
in wto: 200 genes ≥2 fold
Gene
Fold
Ski (Sloan-Kettering viral oncogene)
Ang 3 (angiogenin 3)
Ang 4
Ang 1
Ang 2
10.4
5.8
5.1, 5.1
5.1
3.4
svb9y(vs)wty
in fl26y: 200 genes ≥1.7 fold;
Gene
Fold
Ski
Ang 3
Ang 4
Ang 1
Ang 2
Angptl4 (angiopoietin-like 4)
Agtrap (angiotensin II, type I
12.4
3.8
3.3, 2.6
3.2
2.6
1.7
1.6
receptor associated protein)
Usp30 (ubiquitin-specific protease 30) 4.5
Aldh8a1 (aldehyde dehydrogenase
3.2
8 family, member A1)
Gab3 (growth factor receptor bound
3.0
protein 2-associated protein 3)
Gnao1 (GTP-binding protein
alpha subunit)
Pik3c2g (PI3K, C2 domain
containing,  polypeptide)
Plxna1 (Plexin A1)
Saa2 (serum amyloid A 2)
Saa1
Psca (prostate stem cell antigen)
Slc25a17
Slc4a1
Aldh8a1
2.8
in svb9y: only 51 genes ≥1.5 fold
Gene
Fold
Angptl4
1.7
Agtr1
1.4,1.3
(angiotensin receptor 1)
Usp30
9.6
Aldh8a
1.8
Gab3
7.2
3.0
Gnao1
6.5
2.8
Pik3c2g
1.7
2.8
2.6, 2.0
2.0
2.3
2.2
2.2
Plxna1
Saa2
Saa1
Psca
3.3
2.9,2.5
2.7
3.2
1.9
3.6
Plxna1
Saa2
Saa1
1.7
1.5, 1.5
1.3
Slc25a172.1, 1.7
Slc4a1
Cxcl14
Rkhd1
4.4
1.4
1.7
Rkhd1 (ring finger (C3HC4 type)
2.1
Cxcl14 (chemokine ligand 14)
Rkhd1
and KH domain containing 1)
Fxyd4 (FXYD domain-containing ion
transport regulator 4)
2.0
Fxyd
3.8
Eif4e (eukaryotic translation
initiation factor 4E)
Igfbp6
1.6
Eif4el3
2.0
1.6
Igfbp6
1.3
Shown are some representative genes COMMONLY upregulated in wto and/or fl26y and/or svb9y compared to wty VPs. Gene names and fold increase are
indicated. Some genes showed upregulation on several probesets. Genes marked in red are commonly upregulated in all 3 sets of comparisons.