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Sex Linked Genes Location Sex linked genes are typically located on the X chromosome. No corresponding gene on the Y chromosome. Sex-Linked Traits Hemophilia Color deficiencies Calico cats! Queen Victoria was a carrier for hemophilia Who it affects most Sex linked recessive traits are more likely to affect men than women. Why do you think that happens? Men have only one X chromosome. The Transmission of Sex-Linked Recessive Traits Mother homozygous dominant (XAXA), father has recessive trait (XaY). a. Daughters are carriers, sons normal. Female carrier mates with normal male. b. ½ sons have trait, ½ daughters will be carriers. Female carrier mates with male with recessive trait. c. ½ daughters are carriers, ½ have trait. ½ sons have trait, ½ do not. Red-Green Color Deficit Color deficiencies “Red-Green” deficiency Protanopia, Deuteranopia 1% of males, 0.02 % of females Missing Long wave length cones OR Missing medium wave length cones “Blue-Yellow” deficiency Tritanopia 0.002 % of males, 0.001% of females Missing short wave length cones. X-linked Trait: Calico Cat A gene for fur color resides on the X chromosome. Kiley! After getting spayed X-linked Trait: Calico Cat A yellow cat has a litter of four kittens: 1 yellow and 3 calico. Assuming that there is a single father for the litter, what is the sex of the yellow kitten? Male orange Black Black orange orange Black Black Black orange orange