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A suitcase of clothes Boxes of household goods A fork with coiled spaghetti A bundle of rope A chromosome Biology Chromosomes are pieces of tightly packed “supercoiled” DNA. The DNA is packed up so it can be moved easily. Do you think the DNA in cells is packed up in chromosomes most of the time? Most of the time, DNA is in long loose strands, called chromatin, in the nucleus. The DNA needs to be accessible by enzymes so it can replicate and produce mRNA, which makes proteins. Like shoes, chromosomes come in pairs. Unlike shoes, our pairs of chromosomes are very similar, but not always identical. Why do you think we have un-identical chromosomes that come in pairs? How many chromosomes are pictured? How many homologous pairs are pictured? Chromosomes can be duplicated The 2 copies are identical The two copies are called sister chromatids They are connected at the center at a point called the centromere How many chromosomes are pictured here? How many chromosomes are pictured? How many homologous pairs are pictured? Chromosomes contain many different genes. A gene is a section of DNA that codes for a specific protein or trait. Example- a gene that makes a protein that helps blood clot Some genes have different versions (white flowers or purple flowers) We call the versions alleles. Example: the alleles for hair color in rabbits may be white, brown, etc. Many different organisms have different numbers of chromosomes. This makes sense because we all have different traits, produced by different proteins, which are produced by different genes on your DNA. Mulberries have 308 chromosomes. fruit flies have 8. a dog has 78. Our closest relatives, chimpanzees and gorillas both have 48. Human DNA can be separated into 46 chromosomes. Since chromosomes come in pairs, humans have 23 pairs of chromosomes. People with Down Syndrome have 47 chromosomes because they were born with an extra copy of chromosome #21. They still have 23 pairs of chromosomes, but one of those pairs is a “trio” because it has a 3rd chromosome. MITOSIS AND MEIOSIS