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GENETICS GREGOR MENDEL (1822- 1884) Self Fertilization Offspring= Purebred Cross Fertilization Offspring = Hybrid CROSS POLLINATION HYBRID COCKER SPANIEL + POODLE COCKAPOO HYBRID PUG + BEAGLE PUGGLE HYBRID DOG AND WOLF Liger male lion and a female tiger Peas! GENETIC TERMINOLOGY • Dominant • Recessive • Homozygous • Heterozygous • Genotype • Phenotype • Trait • Allele Dominant and Recessive Alleles • Dominant allele- trait is always expressed if present - Written as capital letter - Ex. Tall= T • Recessive allele- only expressed if no dominant allele is present – (Dominant allele masks this one) - For a particular trait written as the same letter but lower case - Ex. Short= t • Genotype- the genes you get from your parents – Two letters represent the two alleles – One from mom one from dad – TT, Tt, tt • Phenotype- the physical trait, what you look like – Tall short, yellow or green – TT, tt what is the phenotype?? • Homozygous - the same alleles for a gene – TT, tt • Heterozygous - having different alleles for a gene – Tt Trait = Height TALL alleles SHORT Gene- unit of inherited information in DNA Allele- alternative form of a gene ( white purple) Flower Color Trait Test Cross- mate an unknown genotype ( TT or Tt) with homozygous recessive (tt) Reginald Punnett In Starfish being red is dominant over being pink. What would Patrick’s phenotype be? What would his genotype be? Because Patrick is pink… his phenotype is PINK And since pink is recessive – his genotype would be “rr” Red is dominant over pink Suppose we had a HETEROZYGOUS red starfish what would the genotype be? Let’s do some… MONOHYBRID CROSSES! Monohybrid means we are only using ONE TRAIT STEP by STEP 1. Select a “good” letter to use 2. Write down your “givens” 3. Determine parents and record 4. Set up Punnett Square 5. Determine genotypes & phenotypes of offspring (use percentages or fractions) In pea plants being Tall is dominant over being short Cross a Heterozygous Tall plant with a Homozygous Tall plant Aa x AA A A A Geno = 50% AA 50% Aa Pheno = 100% Tall Heterozygous Blue = Bb Recessive Yellow = bb so we cross… Bb x bb Time for some LOONEY Monohybrid Crosses on your own! Red is dominant over Blue T E S T C R O S S MENDELS LAWS 1. Dominance & Recessiveness 2.Segregation 3. Independent Assortment PEDIGREE male female