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SPECIAL TYPES OF CROSSES 1 1. Incomplete Dominance: When the phenotype of offspring result in a BLENDING of the trait. 2 The RED (RR) color of a four o’clock flower is incompletely dominant to the WHITE (rr) colored flower…hybrid offspring will be PINK (Rr). 3 Incomplete Dominance Example: four o’clock flowers red (RR) x white (WW) RR = red flower WW = white flower W W R RW RW R RW RW 4 Incomplete Dominance W W R RW RW R RW RW produces the F1 generation All RW = pink (heterozygous pink) 5 2. Codominance When BOTH alleles for a trait are represented in the heterozygous offspring. 6 The RED (RR) color of hair in horses is COdominant to white hair (WW)…hybrid offspring will have a ‘roan’ coat (RW) color… BOTH red and white hairs (“ROAN”)! 7 Red x White: RR x WW W R R W RW RW RW RW Roan x Roan: RW x RW R W W RR RW R RW WW 8 Genotype: RW Genotype: RR, RW, WW Genotypic Ratio: 4 RW : 0 Genotypic Ratio: 1 RR : 2 RW : 1 WW Phenotype: Roan Phenotype: Red, Roan, White Phenotypic Ratio: 4 Roan : 0 Phenotypic Ratio: 1 Red: 2 Roan: 1 White 9 3. Multiple Alleles – genes for which more than two different alleles exist. Ex: skin color, eye color, hair color, blood type 10 Example: blood type A (dominant), B (dominant) AB (codominant), O (recessive) IA - blood type B I – blood type IAIB – blood type ii – blood type 11 GENOTYPES PHENOTYPES AA Type A AO Type A AB Type AB BB Type B BO Type B OO Type O 12 Codominance Problem Example: A woman heterozygous for type B blood marries a man who is heterozygous type A. What are the possible genotypes and phenotypes of their children? heterozygous female Type B (IBi) x heterozygous male Type A (IAi) IB i Geno – 1 IA IB : IA i IAIB IBi IAi ii 1 IA i : 1 IB i : 1 ii Pheno – 1 Type A : 1 Type B: 1 Type AB: 1 Type O 13 Another Codominance Problem • Example: male Type O (ii) x female type AB (IAIB) IA IB i IAi IBi i IAi IBi 1/2 = IAi 1/2 = IBi 14 Codominance Question: If a boy has a blood type O and his sister has blood type AB, what are the genotypes and phenotypes of their parents? boy - type O (ii) AB (IAIB) X girl - type 15 Codominance Answer: IA IB i i IAIB ii Parents: genotypes = IAi and IBi phenotypes = A and B 16 4. Sex-linked Traits Genes carried only on the sex chromosomes. Ex: color blindness or hemophilia XX genotype for females XY genotype for males 1. Most sex-linked traits are carried on X chromosome 17 1. Most sex-linked traits are carried on X chromosome 2. The Y chromosome in males is small and cannot carry/mask any traits. 3. Therefore, males express sexlinked traits more often than females. ** Males that are affected don’t usually live past a certain age to pass on their traits to offspring. 18 Genotypes XX XX* X*X* XY X0Y Phenotypes Normal Female Carrier Female Affected Female Normal Male Affected Male 19 Sex-linked Traits Example: Eye color in fruit flies Sex Chromosomes fruit fly eye color XX chromosome - female Xy chromosome - male 20 Sex-linked Trait Problem Example: Eye color in fruit flies (red-eyed male) x (white-eyed female) XRY x XrXr Remember: the Y chromosome in males does not carry traits. Xr Xr RR = red eyed Rr = red eyed R X rr = white eyed XY = male Y XX = female 21 Sex-linked Trait Solution: Xr XR XR Xr Y Xr Y Xr XR Xr Xr Y 50% red eyed female 50% white eyed male 22 A woman who is a carrier for colorblindness marries a man who is colorblind. What are the possible genotypes and phenotypes of their children? Genotypes: Phenotypes: 23 Female Carriers 24