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Mendel & heredity http://www.travelchannel.com/shows/ mysteries-at-the-museum/video/bluepeople-roaming-the-hills • Heredity- transmission of traits from parent to offspring. • Genetics- the study of heredity • Gregor Mendel • The “father” of genetics • Austrian monk • Studied the garden pea to develop a set of rules to predict the patterns of heredity. • Mendel used the garden pea because: • It grows quickly • Has many varieties • Able to self-pollinate or true breed Mendel’s experiments • 1. produced a true-breeding P generation (parent) • 2. produced the next generation, F1 (filial) generation, by cross pollinating plants. • 3. produced 3rd generation, F2 (filial) generation by self- pollination • See picture Mendel’s Theories • Mendel thought that certain “factors” were passing on traits. • We now know the factors are genes. • An organism has 2 genes for each trait. • One gene came from the female gamete and one from the male gamete. Meiosis Simple patterns of Heredity aka principle of dominance • Dominant gene- the gene that can cover up a recessive gene • Recessive gene- the gene that can be covered up. • If you have one dominant gene and one recessive gene you will have the dominant trait. • If you have two dominant genes you will have the dominant trait. • If you have two recessive genes you will have the recessive trait. Examples in peas Cross Result Tall X short Tall Green pea X Yellow pea Smooth pea X wrinkled pea Yellow pea Smooth pea • Use Upper case letter for dominant gene • ex- T is for tall pea plant • Use lower case letter for recessive gene • ex- t is for short pea plant • Homozygous- if both genes for the trait are the same ex-TT • Heterozygous- if the genes for the trait are different ex- Tt • Allele- one of the copies of a gene ex- T • Phenotype- the visible trait of the organism. Ex- Tall • Genotype- the combination of genes for a trait. Ex- TT, Tt, or tt Mendel’s Laws • 1. The Law of Segregation: Two alleles for a trait separate during the formation of gametes. • 2. The Law of Independent Assortment: alleles for different traits separate independently of one another during formation of gametes if they are on different chromosomes. • ex- the gene for eye color separates independently of the gene for hair color. • In humans, 6 fingers on one hand is dominant and 5 fingers is recessive. • 1. What is the genotype of an individual that is homozygous dominant? • 2. What is the phenotype of an individual that is homozygous dominant? • 3. What is the genotype of an individual that is heterozygous? • 4. What is the phenotype of an individual that is heterozygous? • 5. What is the genotype of an individual with 5 fingers? Complex Patterns of Inheritance • 1. Incomplete dominance- a heterozygous individual show a trait that is a blend of the 2 genes. • Ex- snapdragons- if flower has a dominant red allele and a recessive white allele the flower is pink. • 2. Codominance- 2 different dominant alleles can be expressed at the same time in heterozygous individuals. • Ex- Roan color in horses. Both red and white hair color genes are dominant. The horse has red hairs and white hairs. • 3. Multiple alleles- some traits have more than 2 alleles that determine it. • Ex- 3 alleles determine blood type A, B, and O Polygenic Inheritance • More than one gene effects the trait. Ex- height, weight, skin color Only about 600 traits in humans are determined only from one gene.