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Section 11-4: Meiosis • • Where are genes located? Chromosomes in the nucleus Basic principles of genetics require 2 things: 1. Each organism must receive a single copy of every gene from both its parents 2. Each organism produces gametes which contain just one set of genes ANIMATION - Square Dance Chromosome Number • Humans have 46 chromosomes • Work in pairs (like shoes) • Homologous chromosomes – sets of chromosomes – How many pairs of chromosomes do humans have? 23 – 23 for Mom + 23 from Dad = 23 pairs Chromosome Number • Diploid – two sets – 2N – Cell that contains both sets of homologous chromosomes – Humans – 2N = 46 • Haploid – Cells that contain a single set of chromosomes – gametes – Humans – N = 23 Phases of Meiosis • Meiosis – reduction division – Go from diploid cells to haploid cells – Chromosome number is cut in half • Meiosis goes thru 2 rounds of division: – Meiosis I and Meiosis II – Diploid cell becomes 4 haploid cells (gametes) • Males – sperm - Females – egg Meiosis I • Chromosomes (DNA) are replicated before division • Prophase I – like in Mitosis • Metaphase I – chromosomes line up at center …But in PAIRS! – called a tetrad – Crossing-over – portions of chromatids are exchanged • Anaphase I – homologous pairs are separated • Telophase I & Cytokinesis – 2 Daughter Cells Meiosis II • • • • 2 Cells produced by Meiosis I enter Meiosis II Chromosomes are NOT replicated Just like 2 cells going thru mitosis Result is 4 haploid daughter cells Comparing Mitosis and Meiosis • Mitosis produces 2 genetically identical diploid daughter cells • Meiosis produces 4 genetically different haploid daughter cells SQUARE DANCING Nondisjunction Karyotype of a normal male Karyotype of a Patau’s male (notice chromosome #13 has Questions 1. An organism has 24 chromosomes and cell division occurs. The resulting cells have 24 chromosomes and are described as __________ 2. With regard to #1 cells divide elsewhere in the body and resulting cells have 12 chromosomes and are described as ______________. 3. What name(s) are given to the cells that have 12 chromosomes.