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GENETICS IN A NUTSHELL BY: LINDA HEIDENRICH BIOLOGY THE BASICS Dominant: represented by a large letter; trait that is expressed Recessive: represented by a small letter; trait that is masked unless in the homozygous form Genotype: genes in an organism Phenotype: outer appearance from the genes MORE BASICS AA=homozygous dominant Aa=heterozygous aa=homozygous recessive AA or Aa=dominant trait aa=recessive trait Autosomal Trait An autosome is a gene found in the body cells, i.e. not found on sex chromosomes. Genetics follow basic heredity rules regarding dominance and recessiveness. EXAMPLE: Mendel’s peas Combine TT (homozygous tall) and Tt (heterozygous tall)…What do you get? Welcome the Punnett Square A Punnett Square explains the possible outcomes for a mating. T T T TT TT t Tt Tt So… A cross between a homozygous tall and a heterozygous tall would yield… – 50% probability of getting homozygous tall plants as offspring – 50% probability of getting heterozygous tall plants as offspring HOW do you get a short plant? – Think, Pair, Share Well… Either cross tt x tt or Tt and tt Try the Punnett Square for each… T t t t Sex-Linked Trait on a gene found on X or Y chromosome Usually are recessive disordersapparent only in the homozygous recessive form Common example: red-green colorblindness in boys or hemophilia Sex-Linked Trait Notation Notation: – – – – – Male with trait: XhY Male without trait: XHY Female with trait: XhXh Female without trait: XHXH Carrier female: XHXh TRY ONE: Cross a hemophiliac male and a carrier female. Incomplete Dominance Autosomal traits BUT the heterozygous phenotype is a combination of the two homozygous phenotypes Example: Color in snapdragons – RR=red – Rr=pink – rr=white TRY ONE: Cross a pink snapdragon with a red flower. Co-dominance Autosomal traits BUT the heterozygous is BOTH homozygous traits. NO RECESSIVE Example: Horse Coloring – RR=Red – RR’=Red/White (Roan) – R’R’=White TRY ONE: Cross a two roan horses. Blood Types Combination of Co-dominance and dominant and recessive patterns – AB blood: IA IB – A blood: IA IA or IA i – B blood: IB IB or IB i – O blood: ii TRY ONE: Cross a heterozygous A blood female with a homozygous B blood male.