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Warm-up Problem: Autosomal Recessive
Steve and Linda have a history of cystic fibrosis (CF) in
their families. Steve is a carrier of CF and Linda is
heterozygous. They always wanted a family with
three children (make the children any gender you
wish).
a. Complete a Pedigree showing these 5 people.
b. Complete a Punnett square for Steve & Linda.
c. What is the probability for having a healthy child?
d. What is the probability that all three children will
be healthy?
Warm-up Problem: Autosomal Recessive
Steve and Linda have a history of cystic fibrosis (CF) in their families.
Steve is a carrier of CF and Linda is heterozygous. They always wanted
a family with three children (make the children any gender you wish).
¾
Steve
healthy
Steve
Linda
Hh
Hh
¾
Lind
a
healthy
H h
Hh
H Steve
HH Steve
Hh Steve
hh
h Steve
a. Complete a Pedigree showing
these 5 people.
¾
Steve
b. Complete a Punnett square for
Steve & Linda.
healthy
c. What is the probability for
having a healthy child?
3/4
d. What is the probability that all
three children will be healthy?
27/64
Warm-up Problem: Autosomal Dominance
Rodney recently tested negative for the FH gene even
though his mother and father had FH. Francine
recently survived a heart attack at 34 years of age.
They have two children who were recently tested
negative for the FH gene.
a. Complete a Pedigree showing these 6 people.
b. Complete a Punnett square for Rodney & Francine.
c. What is the probability for having a healthy child?
d. What were the odds of Rodney being born without
the FH gene?
Warm-up Problem: Autosomal Dominance
Rodney recently tested negative for the FH gene even though his
mother and father had FH. Francine recently survived a heart attack
at 34 years of age. They have two children who were recently tested
negative for the FH gene.
a. Complete a Pedigree
showing these 6 people.
Hh
¾
hh
b. Complete a Punnett
square for Rodney &
Francine.
Hh
Rodney
Francine
hh
Hh
healthy
c. What is the probability
for having a healthy
child?
hh
d. What were the odds of
Rodney being born
without the FH gene?
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