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Gregor Mendel Book: “Experiments in Plant Hybridization” Why Mendel was successful… He studied single traits He used LARGE sample sizes Introduced Ratios Terms to KNOW Allele: 1 of 2 or more different forms of a gene. Represented as a letter. 2 alleles make a genotype. Genotype: Genetic Make-up represented as 2 alleles, one from each parent. Ex: “AA, Aa, aa” Phenotype: Physical Characteristic. Ex: Blue eyes. Dominant: Allele that will be expressed. Represented as a capital letter. Ex: “A” Recessive: Allele that is “hidden.” Represented as a lower case letter. Ex: “a” Homozygous: 2 of the same alleles Example: AA or aa Heterozygous: 2 different alleles Example: Aa MORE Terms to Know Monohybrid: Individual that is heterozygous for one trait. Ex: Aa Monohybrid Cross: Genetic Cross between 2 heterozygotes. Ex: Aa x Aa First and Second Parental Generations P1 and P2 First and Second Filial Generations (offspring- filial means child in Latin) F1 and F2 Law of Dominance: If a dominant allele is present, the dominant phenotype will be expressed. Model Genotype symbol Genotype description Phenotype Type of organism that exhibits genotype RR Homozygous Dominant Round Pure bred rr Homozygous recessive Wrinkled Pure bred Rr Heterozygous Round Hybrid Law of Segregation During the formation of gametes (in meiosis), alleles of gametes separate (segregate). Each G allele has separated from the other. Punnett Square Diagram showing the possible combinations of offspring from a genetic cross r r R Rr Rr Parents Offspring R Rr Rr Pisum sativum Pea Plants P1= round (RR) x wrinkled (rr) F1 = round (Rr) r r R Rr Rr R Rr Rr P2= round (Rr) x round (Rr) F2 = 5,474 round, 1,750 wrinkled R r R RR Rr r Rr rr Types of Ratios 1. 2. Genotypic Homozygous Dominant : Heterozygous: Homozygous Recessive Phenotypic Dominant : Recessive Example: genotypic ratio R R r R RR RR Rr Rr 2:2:0 or ________ 1:1:0 ; phenotypic ratio 4:0 or _______ 1:0 Monohybrid Cross Ratios R r Genotypic Ratio: R RR Rr 1:2:1 Phenotypic Ratio: r Rr rr 3:1