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the biomarker company™
Delivering Biomarker Discovery Data to
Customers and Collaborators using Posters
Keith Joho, Ph.D.
Vice President, Informatics and Bioanalytical Operations
Spotfire User Conference 10-15-03
Biomarker Discovery
Homocysteine Cholesterol
PSA CRP
?
?
Glucose
TG Insulin HbA1C ?
Her2 CD4+ Clinical
Cells T-cells Phenotype
Complex
Systems
Simple molecules
metabolites
carbohydrates
steroids
lipids
peptides
proteins
protein complexes
SurroMed Technologies:
mRNA/genes
cells
Mass Spectrometry
Low MW (Metabolome)
Immunoassays
Proteome Gene
patients
chip
Cytometry (SurroScanTM cytometer)
eCRF, eMR
Spotfire User Conference 10-15-03
SurroMed Data Warehouse
LIMS
Oracle
Clinical
•eCRF
•EMR
ELISA
Mass Spectrometry
•Proteomic
•Metabolomic
Spotfire User Conference 10-15-03
Cytometry
SurroStat™ Architecture
CLIENTS
HTTP/ HTTPS
Web Server
Sun ONE
J2EE Application
Server
S-Plus AS
JDBC
SurroStat
Posters
™
Decision Site
Servlets EJB
Spotfire User Conference 10-15-03
JSP
Oracle
SurroStat™ Spotfire Integration
Spotfire User Conference 10-15-03
SurroMed Posters Architecture
Customer A
Publish
HTTPS
Customer B
HTTPS
DecisionSite
Server
DecisionSite
Server
Posters
Posters
(Production)
(Internal)
HTTPS
Customer C
User Profile
Database
Posters
Repository
Internet
Spotfire User Conference 10-15-03
DMZ
Posters
Repository
User Profile
Database
Surromed
Internal
Network
Data Warehouse
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