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Chapter 10: Patterns of Inheritance Concept 10.1 Genetics Developed from curiosity about inheritance… Vocab • Trait • Genetics • Cross Fertilization Blending Theory • • • • Early 1800’s Blue x Red = Purple Purple always produce purple Problems with theory… Gregor Mendel • • • • • • Austrian Monk Taught High School Biology Mathematician Lived in a Monestary Bred Pea Plants in Garden Crossed generations for 7 years Mendel’s Theory • Particulate Hypothesis – True-breeding – Led to “Genetics” • Used self- vs. cross-fertilization Concept 10.2 Mendel discovered that inheritance follows rules of chance… Vocab • • • • • • • Hybrids Monohybrid cross Allelese Homozygous Heterozygous Dominant Recessive • • • • • Phenotype Genotype Testcross Dihybrid cross Principle of Segregation • Principle of Independent Assortment • Generations Principle of Segregation • True breeding=pure (homozygous) • True x true = hybrid Pea Traits: • • • • • Allele= purple vs. white Dominant= Capital (B) Recessive= Lowercase (b) Homozygous= BB or bb Heterozygous = Bb Principle of Segregation • Alleles separate into different gametes during meiosis… Probability • The mathematical prediction that a specific event will occur! • Written as fractions, decimals, or percents! Genotype vs. Phenotype • Genotype= Gene Combination (BB, Bb, or bb) • Phenotype= What it looks like (Black vs. Fawn) Testcross: • Cross between one known parent and one unknown parent to determine the genotype of the unknown. 10.4 Meiosis Explains Mendel Chromosome Theory of Inheritance • Genes are located on chromosomes • Chromosome behavior accounts for inheritance • Chromosomes undergo segregation and independent assortment Reminder…Karyotype Gene Locus • Each gene has a specific location on each chromsome Genetic Linkage • Same chromosome = genes linked – Unless crossing over occurs • Blue eyes paired with blonde hair • Brown eyes paired with brown hair 10.5 Sex-linked traits have unique inheritance patterns… Sex Linked Genes • A gene that is located on the sex chromosome • Discovered by Thomas Hunt Morgan – Studied eye color in fruit flies • Result in unusual inheritance ratios (patterns) Sex-Linked Disorders • Red-green color blindness, hemophilia, male pattern baldness, etc. • Recessive traits more common in men! – Usually allele is absent on the y chromosome