Download Chapter 24 Nursing Care of Patients with Hematopoietic

Document related concepts
no text concepts found
Transcript
Nursing Care of Patients with Hematologic
and Lymphatic Disorders

Deficiency of Red Blood Cells, Hemoglobin, or
Both
◦ Impaired Production
◦ Increased Destruction
◦ Blood Loss

Reduced Capacity to Carry Oxygen to Tissues



Dietary Deficiencies
Hemolysis
Hereditary Disorders






Pallor
Tachycardia
Tachypnea
Irritability
Fatigue
Dyspnea

Pernicious Anemia
◦ Numb Hands or Feet
◦ Sore Tongue

Iron Deficiency
◦ Mouth Fissures
◦ Glossitis
◦ Spoon-shaped Nails



CBC with Microscopic Examination
Bone Marrow Analysis
Tests to Determine Source of Bleeding




Eliminate Cause
Dietary Changes
Supplements
Transfusions




Activity Intolerance
Imbalanced Nutrition
Risk for Injury
Impaired Oral Mucous Membranes


Bone Marrow Does not Produce Adequate
RBCs
Causes
◦ Congenital
◦ Exposure to Toxins
◦ Chemotherapy





Weakness
Fatigue
Pallor
Dyspnea
Headache





Ecchymoses
Petechiae
Frank Bleeding
Infection
Death

Diagnosis
◦
◦
◦
◦
CBC
Bone Marrow Biopsy
TIBC
Serum Iron

Treatment
◦ Treat Cause
◦ Colony Stimulating
Factors
◦ Steroids
◦ Bone Marrow
Transplant

Inherited
Autosomal
Recessive Disorder

Diagnosis
◦ Sickledex Test
◦ Hemoglobin
Electrophoresis
◦ CBC
◦ ESR

Crisis Treatment
◦
◦
◦
◦
◦
Antibiotics
Pain Management
Transfusions
Fluids
Oxygen

Avoid Risk of Reduced Oxygenation
◦ Exposure to Cold
◦ Infection
◦ Strenuous Exercise



Low Dose Penicillin
Frequent Transfusions
Hydroxyurea


Risk for Ineffective Tissue Perfusion
Acute Pain

Avoid
◦
◦
◦
◦
◦
◦
◦
Tight Clothing
Strenuous Exercise
Alcoholic Beverages
Cold Temperatures
Smoking
Unpressurized Aircraft
Exposure to Infection




Overabundance of Red Cells
Hemoglobin >18 mg/dL
Hematocrit >55%
Blood Becomes Thick
◦ Primary
◦ Secondary






Hypertension
Visual Changes
Headache
Vertigo
Dizziness
Tinnitus





Bleeding
Chest Pain
Dyspnea
Dark, Flushed Skin
Itching




Phlebotomy
Low Dose Aspirin
Chemotherapy
Radiation Therapy





Drink 3 Liters of Water Daily
Avoid Restrictive Clothing
Elevate Feet
Report Signs and Symptoms of Iron
Deficiency
Report Signs and Symptoms of Bleeding

Pathophysiology
◦ Accelerated Clotting
◦ Clotting Factors Depleted
◦ Bleeding

Etiology
◦ Major Trauma







Abnormal Bleeding
Joint Pain
Nausea and Vomiting
Organ System Failure
Convulsions
Shock, Coma
Death






Easy Bruising
Petechiae
Blood in Urine
Black Tarry Stools
Bleeding from Nose or Gums
New Onset of Painful Joints




PT, PTT
Platelet Count
Hbg
Hemoglobin, Creatinine


Correct Underlying Cause
Administer
◦
◦
◦
◦
Blood
FFP
Platelets
Cryoprecipitates



Recognize and Report Bleeding
Avoid Trauma and Further Bleeding
Teach Patient and Family

Pathophysiology
◦ Platelet Destruction by Immune System
◦ Risk for Bleeding

Etiology
◦ Acute Viral Illness
◦ Drug Reaction
◦ Immune System Dysfunction

Bleeding
◦ Petechiae
◦ Ecchymoses
◦ Bleeding



Platelet Count
Bleeding Time
Bone Marrow Aspiration






Steroids
Chemotherapy
Transfusions
Vitamin K
Chemotherapy
Splenectomy



Bleeding Precautions
Recognize and Report Signs and Symptoms
Bleeding
Teach Patient and Family





Use Electric Razor
Use Soft Toothbrush
Avoid Invasive Procedures, Injections
Maintain Pressure if Blood Draw Essential
Wear Shoes or Slippers





Avoid Bumps and Bruises
Avoid Aspirin and Nsaids
Administer Stool Softener
Handle Patient Gently
Gentle Nose Blowing

Pathophysiology
◦ Missing Clotting Factors
 A—Factor VIII
 B—Factor IX

Etiology
◦ Heredity

Bleeding
◦
◦
◦
◦
Joints
Muscles
Subcutaneous Tissue
Brain


PTT
Factor Levels


Desmopressin
Clotting Factors
◦ Factor VIII
◦ Factor IX

Blood Transfusion



Pain
Ineffective Protection
Risk for Ineffective Self Health Management

Pathophysiology
◦ Increase in Immature WBCs
◦ Unable to Fight Infection

Risk Factors
◦ Viruses
◦ Genetic Factors
◦ Radiation/Chemotherapy




Acute Lymphocytic Leukemia
Acute Myelogenous Leukemia
Chronic Lymphocytic Leukemia
Chronic Myelogenous Leukemia






Fever
Infection
Pallor
Weakness
Tachycardia
Palpitations






Dyspnea
Abdominal Pain
Malaise
Sternal/Rib Pain
CNS Changes
Bleeding




CBC
Bone Marrow Aspiration
Lumbar Puncture
Genetic Analysis




Chemotherapy
Radiation Therapy
Bone Marrow Transplant
Peripheral Blood Stem Cell Transplant





Risk for Injury: Infection, Bleeding
Fatigue
Impaired Oral Mucous Membranes
Knowledge Deficit
Anxiety

Pathophysiology
◦ Cancer of Plasma Cells in Bone Marrow
◦ Tumors Devour Bone Tissue
◦ Organ Invasion

Etiology
◦ Unknown
◦ Occupational Exposures







Bone Pain
Fever
Malaise
Spinal Cord Compression
Pathological Fractures
Hypercalcemia
Infection




CBC, Blood Calcium
Bone X-Rays
Urine for Bence
Jones Protein
Bone Marrow Biopsy






Steroids
Chemotherapy
Control of Serum Calcium
Radiation
Stem Cell Transplantation
IV Pamidronate (Aredia)


Risk for Infection
Risk for Injury
◦ Fracture
◦ Complications of Immobility
◦ Hypercalcemia

Cancer of Lymph System
◦ Presence of Reed-Sternberg Cells

Etiology
◦ Viral
◦ Genetic
◦ Immune Dysfunction







Painless Swollen Lymph Node
Pruritis
Pain Induced by Alcohol
Fever
Night Sweats
Weight Loss
Malaise





Edema of Face and Neck
Jaundice
Nerve Pain
Retroperitoneal Node Involvement
Spleen, Liver, and Bone Involvement

Biopsy
◦ Lymph Node
◦ Liver and Spleen
◦ Bone Marrow





CT, Chest X-Ray
Lung
Bone Scan
Lymphangiography
CBC




Stage I: Single Lymph Node or Site
Stage II: Two or More Nodes on Same Side of
Diaphragm
Stage III: Nodes on Both Sides of Diaphragm
Stage IV: Widely Disseminated Disease in
Organs or Tissues


Chemotherapy
Radiation Therapy




Impaired Comfort
Activity Intolerance
Risk for Infection
Risk for Ineffective Coping



Lymphoma Arising from B Cells and T Cells
Absence of Reed-Sternberg Cells
Etiology
◦
◦
◦
◦
Some Viruses
H Pylori
Immune Dysfunction
Occupational Exposures



Painless Lymph Nodes
Enlarged Tonsils and Adenoids
Other Signs and Symptoms Similar to
Hodgkin’s Disease

Biopsy
◦
◦
◦
◦
◦
Lymph Nodes
Tonsils
Bone Marrow
Liver
Other







Bone Scan
CT, Chest X-ray,
IVP
MRI, PET Scan
Lymphangiography
CBC
Liver Function
Studies
Serum Calcium





Chemotherapy
Monoclonal Antibodies
Interferon Therapy
Radiation Therapy
Stem Cell Transplant



Activity Intolerance
Risk for Infection
Risk for Ineffective Coping

Hodgkin’s
◦ Less Common
◦ Age 15 to 40 and
>55
◦ Reed-Sternberg Cells
◦ Younger
◦ Good Prognosis
◦ Alcohol-induced Pain

Non-Hodgkin’s
◦ More Common
◦ Usually >Age 50
◦ Absence of ReedSternberg Cells
◦ Poorer Prognosis
Surgical Removal of the Spleen





Baseline Labs
Blood Transfusion if Necessary
Vitamin K
Baseline Vital Signs
Teach Coughing and Deep Breathing




Monitor for Bleeding
Monitor Vital Signs
Administer Narcotics for Pain
Encourage to Cough and Deep Breathe and
Ambulate





Bleeding
Pneumonia
Atelectasis
Infection
OPSI