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Cellular Apoptosis pathway Akt Signaling pathway p53 pathway Caspase3 MEKK2 Inhibition of Matrix Metalloproteinases (MMPs) MEKK1 EGF pathway VEGF Family ligands and Receptor interactions Antibodies Clonality Applications active Caspase 3 P active Caspase 3 ADAM10 ADAM17 AKT1 (phospho S473) ATM (phospho S1981) ATM [2C1 (1A1)] B Raf [EP152Y] Bad (phospho S136) Bax Bcl2 Bmi1 Caspase 9 CCR2 CDKN2A/p19ARF c-Fos c-Myc (phospho T58) E Cadherin [DECMA-1] E2F1 EGFR ErbB 2 ERK1 + ERK2 Estrogen Receptor alpha [33] M P P P P M M P P P P P P P P P P P P P P M Estrogen Receptor beta Fibronectin [IST-9] P M Flow Cyt, ICC, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IHC (PFA fixed), WB WB WB WB Dot Blot, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB ICC/IF, WB IHC-P, IP, WB Flow Cyt, IHC-P, IP, WB ELISA, IHC-P, WB IHC-Fr, IHC-P, IP, WB ICC/IC, IHC-P, WB ICC/IF, WB WB Flow Cyt, IHC-P, WB ELISA, ICC, ICC/IF, IHC-Fr, IHC-P, WB IHC-Fr, IHC-Fr, IHC-P, WB ELISA, ICC/IF, IHC-P, IP, WB Flow Cyt, ICC/IF, IHC-Fr, Inhibition Assay, IP, WB IHC-P, WB IHC-Fr IHC-P, WB ICC/IF Gel supershift assays, ICC/IF, IHC-P, IP, Real Time PCR, WB ELISA, ICC/IF, WB ICC/IF, IHC-Fr, IHC-P, RIA, WB Host Species reactivity Rb Hu, Ms, Rt, Dm, InMtj, RMk, Xl, Zfsh Hu Hu Hu Hu, Ms, Rt Hu Hu, Ms, Rt, Mk Hu, Ms, Rt Hu, Ms Hu, Ms, Rt Hu, Ms Hu Hu Hu, Ms, Rt Ms Hu, Ms, Rt Hu, Ms Hu, Ms, Cow, Dog Hu Ms, Rt Hu Hu, Ms, Rt Rb Rb Rb Rb Rb Ms Rb Rb Rb Rb Rb Rb Rb Rb Goat Rb Rt Rb Rb Rb Rb Ms Rb Ms Product code ab13847 ab77973 ab84595 ab77820 ab66138 ab79891 ab78 ab33899 ab28824 ab7977 ab18210 ab63767 ab90236 ab21667 ab80 ab87655 ab28842 ab11512 ab94888 ab15669 ab38851 ab94484 Hu, Ms, Rt, Cow, Dog Hu Hu, Ms, Rt, Chk, Cow, Dog, Mk, Pig GSK3 beta (phospho S9) [EPR2286Y] HIF1 alpha HIF2 alpha Hsp27 (phospho S86) JNK1 + JNK2 MDM2 MMP2 MMP9 mTOR [53E11] MUC1 MUC1 N Cadherin NFkB p105 / p50 - ChIP Grade NFkB p65 p21 p53 [PAb 240] M P P P P P M P M P P P P P P M pan Cadherin [mAbcam22744] pan-AKT (phospho T308) PTEN [Y184] Ras ROCK1 Survivin Telomerase reverse transcriptase TIE2 TIMP1 [102D1] TIMP2 [3A4] TNF alpha VEGF [VG-1] VEGF Receptor 1 VEGF Receptor 2 M P M P P P P P M M P M P P Proteins Description APRIL protein c-Jun protein (His tag) CTGF protein (Active) MMP2 protein (Human) Caspase 8 protein (Active) Recombinant Murine APRIL, a 21.9 kDa protein, 192 amino acids Recombinant full length Human c-Jun (amino acids 1-331) with His tag, expressed in a baculovirus system Recombinant fragment, corresponding to amino acids 253-350 of Human CTGF Full lenght Human MMP2 purified from human fibroblast cell culture media Recombinant active full length mouse Caspase 8 Biochemicals Size Description Phorbol 12-myristate 13-acetate Z-VAD-FMK Z-D(OMe)E(OMe)VD(OMe)-FMK LY 294002 PP2 Rottlerin 1mg, 5mg, 25mg 1mg, 5mg 1mg, 5mg 5mg, 25mg 1mg, 10mg, 50mg 10mg,50mg PKC activator Irreversible general caspase inhibitor Cell permeable caspase-3 inhibitor PI-3 kinase inhibitor Src and RIP2 kinase inhibitor Kinase inhibitor ICC, IHC-P, WB ICC/IF ICC/IF, IHC-P, WB ICC/IF, WB WB ICC/IF, WB IHC-P IHC-P, WB WB ICC/IF, IHC-P, WB ICC/IF, IHC-P, WB Flow Cyt, ICC/IF, IHC-Fr, IHC-P, WB ChIP, Flow Cyt, IHC-Fr, IHC-P, IF, IP, WB ICC/IF, IHC-FoFr, IHC-P, IP, WB ICC/IF, IHC-P, Sandwich ELISA, WB ELISA, Flow Cyt, ICC, ICC/IF, IHC (Methanol fixed), IHC-Fr, IHC-P, IP, WB ICC/IF, IHC-P, WB ELISA, IHC-P, WB Flow Cyt, ICC/IF, IP, WB WB ICC/IF, WB ICC/IF, IHC-FoFr, IHC-P, WB ICC/IF, WB WB ICC/IF, IHC-Fr, IHC-P, WB IHC-P, WB IHC-Fr, IHC-P, WB ELISA, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB Electron Microscopy, ICC/IF, IHC-Fr, IHC-P, WB ICC/IF, IHC-FoFr, IHC-P, WB ab2746 ab78946 ab6328 Rb Rb Rb Rb Rb Rb Ms Rb Ms Rb Rb Rb Rb Rb Rb Hu Hu Hu, Rt Hu Hu Hu Hu Hu Hu, Ms, Rt Hu Hu Hu, Ms, Rt, Xl Hu, Ms, Rt Hu, Ms, Rt, Chk, InMtj Hu, Rt, Cow ab75814 ab103063 ab20654 ab93059 ab85139 ab87134 ab86607 ab73734 ab87540 ab84597 ab94653 ab18203 ab7971 ab16502 ab18209 Ms Ms Rb Rb Rb Rb Rb Rb Rb Ms Ms Rb Ms Rb Rb Hu, Ms, Rt, Dog Hu, Ms, Rt, AGMk Hu, Ms, Rt Hu, Ms, Rt Hu, Ms, Rt, Cow Hu Hu, Ms, Rt Hu Ms, Rt Hu Hu, Ms, Rt, Cow, Gpig, Rb Hu, Ms, Rt Hu, Ms, Rt, Dog Hu, Ms, Rt, Pig Hu, Ms, Rt ab26 ab22744 ab38449 ab32199 ab69747 ab105107 ab24479 ab94523 ab71712 ab1827 ab109708 ab66579 ab1316 ab2350 ab39256 Product code Raf HIF Pathway Proteasome Ub PCNA MDM2 p53 Ub Ub PKC- MKK4 MKK7 Caspase Cascade & Apoptosis APAF1 UV, Ionizing Radiation UV, Ionizing Radiation Ub Ub p53 δ p53 Degradation Osmotic Shock UV, Ionizing Radiation MEKs BAX Ub Ub Ub BCL2 Double Strand Breaks HIPK2 DNA-PK JNK1 p38 ab50096 ab84134 ab50044 ab40964 ab61298 ERKs BAX DNA Damage Product code PCAF CDC25A CHK 1,2 p38 P P p53 P ATM/ATR P P CSNK2 p53 Sirt P ATM/ATR CSNK δ P p53 GADD45 MDM2 Ubiquitin Proteolysis HDAC BRCA p53 P CDC14 p300 ab120297 ab120382 ab120488 ab120243 ab120308 ab120377 p53 TBP CDK4 Cyclin-D1 PCNA MDM2 Secondary antibodies PIAS p21 PML Transcription CDK2 PCNA Cyclin-E P Rb G1 S G2 M P E2F P Rb And for superb IF and ICC results use our pre-adsorbed secondary antibodies Available conjugated to: Cy3® and Cy5® DyLight® 488, DyLight® 550, DyLight® 594, DyLight® 650 AMCA, FITC, PE, Texas Red® and TRITC Key: AGMk - African Green Monkey | Chk - Chicken | Dm - Fruit Fly (Drosophila melanogaster) | Gpig - Guinea Pig | Hu - Human | InMtj - Indian Muntjac | Mk- Monkey | Ms - Mouse | Rb - Rabbit | RMk - Rhesus Monkey | Rt- Rat | Xl - Xenopus laevi | Zfsh - Zebrafish Cancer pathways Copyright © 2012 Abcam, All Rights Reserved. The Abcam logo is a registered trademark. All information / detail is correct at time of going to print. DyLight® is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. 045_12_AH Discover more at abcam.com/cancer
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